Attenuation of Avian Flavivirus by Rewiring the Leucine and Serine Codons of Its E-NS1 Protein toward Stop Mutation To Redirect Virus Evolution
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DOI: 10.1128/spectrum.02921-22
Abstract: Flaviviruses are medically important arboviruses that threaten public health, but no approved treatments are currently available. Vaccines prevent flavivirus infection. ABSTRACT Recently, a new strategy for attenuating RNA viruses by redirecting their evolution in sequence… read more here.
Keywords: cqw1 ots; attenuation; sequence space; flavivirus ... See more keywords