CR6-interacting factor 1 deficiency reduces endothelial nitric oxide synthase activity by inhibiting biosynthesis of tetrahydrobiopterin
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DOI: 10.1038/s41598-020-57673-9
Abstract: Downregulation of CR6 interacting factor 1 (CRIF1) has been reported to induce mitochondrial dysfunction, resulting in reduced activity of endothelial nitric oxide synthase (eNOS) and NO production in endothelial cells. Tetrahydrobiopterin (BH4) is an important… read more here.
Keywords: biosynthesis; endothelial nitric; crif1; cr6 interacting ... See more keywords