Engineered Cross-Linking to Study the Pore Architecture of the CRAC Channel.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8704-7_13
Abstract: ORAI1 constitutes the pore-forming subunit of the calcium release-activated calcium (CRAC) channel, a prototypical store-operated channel that is essential for the activation of cells of the immune system. Here we describe a convenient yet powerful… read more here.
Keywords: architecture crac; crac channel; pore architecture; cross linking ... See more keywords
CRAC channels in secretory epithelial cell function and disease.
Sign Up to like & getrecommendations! Published in 2019 at "Cell calcium"
DOI: 10.1016/j.ceca.2018.12.010
Abstract: The receptor-evoked Ca2+ signal in secretory epithelia mediate many cellular functions essential for cell survival and their most fundamental functions of secretory granules exocytosis and fluid and electrolyte secretion. Ca2+ influx is a key component… read more here.
Keywords: receptor evoked; ca2 signal; crac; cell ... See more keywords
A qualitative transcriptional signature for determining the grade of colorectal adenocarcinoma
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DOI: 10.1038/s41417-019-0139-1
Abstract: Histological grading (HG) is an important prognostic factor of colorectal adenocarcinoma (CRAC): the high-grade CRAC patients have poorer prognosis after tumor resection. Especially, the high-grade stage II CRAC patients are recommended to receive adjuvant chemotherapy.… read more here.
Keywords: high grade; grade; crac; gene pairs ... See more keywords
Novel adsorbents for the removal of toxic cadmium ions from polluted water.
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DOI: 10.1080/15226514.2022.2137101
Abstract: Cadmium is one of the most toxic heavy metal ions found in wastewaters and its remedial methods are globally investigated. Removal methods based on biomaterials as adsorbents are proving to be simple, effective and eco-friendly.… read more here.
Keywords: adsorption; cadmium ions; crac; extraction ... See more keywords
Orai3 and Orai1 mediate CRAC channel function and metabolic reprogramming in B cells
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DOI: 10.7554/elife.84708
Abstract: The essential role of store-operated Ca2+ entry (SOCE) through Ca2+ release-activated Ca2+ (CRAC) channels in T cells is well established. In contrast, the contribution of individual Orai isoforms to SOCE and their downstream signaling functions… read more here.
Keywords: crac channel; crac; channel function; metabolic reprogramming ... See more keywords