Review: Structure and Activation Mechanisms of CRAC Channels.
Sign Up to like & getrecommendations! Published in 2020 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-12457-1_23
Abstract: Ca2+ release activated Ca2+ (CRAC) channels represent a primary pathway for Ca2+ to enter non-excitable cells. The two key players in this process are the stromal interaction molecule (STIM), a Ca2+ sensor embedded in the… read more here.
Keywords: structure; crac channels; ca2; activation mechanisms ... See more keywords
Targeting CRAC channels in inflammatory bowel disease
Sign Up to like & getrecommendations! Published in 2022 at "EMBO Molecular Medicine"
DOI: 10.15252/emmm.202216489
Abstract: Inflammatory bowel disease (IBD) is a collective term for inflammatory diseases of the human gastrointestinal (GI) tract that are characterized by perturbations in the intestinal immune responses. In their study, Letizia et al (2022) found an enrichment… read more here.
Keywords: inflammatory bowel; targeting crac; crac channels; channels inflammatory ... See more keywords