Defining the critical period of hedgehog pathway inhibitor‐induced cranial base dysplasia in mice
Sign Up to like & getrecommendations! Published in 2020 at "Developmental Dynamics"
DOI: 10.1002/dvdy.270
Abstract: The hedgehog signaling pathway is critical for developmental patterning of the limb, craniofacial and axial skeleton. Disruption of this pathway in mice leads to a series of structural malformations, but the exact role and critical… read more here.
Keywords: defining critical; mice; critical period; cranial base ... See more keywords
Chiari I Malformation and Basilar Invagination in Fibrous Dysplasia: Prevalence, Mechanisms, and Clinical Implications
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.3531
Abstract: Fibrous dysplasia (FD) is a mosaic disorder of benign fibro‐osseous lesions, which may be associated with extraskeletal features as part of McCune‐Albright syndrome (MAS). Cranial base abnormalities, including Chiari I malformation (CM1), in which the… read more here.
Keywords: basilar invagination; base abnormalities; base; fibrous dysplasia ... See more keywords
Locomotion and basicranial anatomy in primates and marsupials.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of human evolution"
DOI: 10.1016/j.jhevol.2017.07.003
Abstract: There is ongoing debate in paleoanthropology about whether and how the anatomy of the cranium, and especially the cranial base, is evolving in response to locomotor and postural changes. However, the majority of studies focus… read more here.
Keywords: primates marsupials; locomotion; anatomy; anatomy primates ... See more keywords
Impact of conflict-induced stress on the length of craniofacial growth.
Sign Up to like & getrecommendations! Published in 2025 at "Scientific reports"
DOI: 10.1038/s41598-025-29888-1
Abstract: In this study, we investigated the effect of chronic environmental stress, due to long-term residence in a conflict zone, on the lengths of the anterior and posterior cranial base, maxilla, and mandible in healthy children… read more here.
Keywords: length; craniofacial growth; conflict; cranial base ... See more keywords
Anterior Cranial Base Reconstruction in Complex Craniomaxillofacial Trauma: An Algorithmic Approach and Single-Surgeon's Experience
Sign Up to like & getrecommendations! Published in 2022 at "Archives of Plastic Surgery"
DOI: 10.1055/s-0042-1744406
Abstract: Management of traumatic skull base fractures and associated complications pose a unique reconstructive challenge. The goals of skull base reconstruction include structural support for the brain and orbit, separation of the central nervous system from… read more here.
Keywords: reconstruction; anterior cranial; cranial base; approach ... See more keywords
A Craniometric Analysis of the Posterior Cranial Base After Posterior Vault Distraction.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Craniofacial Surgery"
DOI: 10.1097/scs.0000000000005496
Abstract: BACKGROUND Posterior vault distraction osteogenesis (PVDO) has been demonstrated to effectively increase intracranial volume, treat increased intracranial pressure, and improve head shape in syndromic patients. The purpose of this study is to compare changes along… read more here.
Keywords: posterior cranial; posterior vault; cranial base; distraction ... See more keywords
The Frequency of Cranial Base Fractures in Lethal Head Trauma
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Forensic Sciences"
DOI: 10.1111/1556-4029.14149
Abstract: The interpretation of cranial base injuries has never been investigated from a purely anthropological perspective. Very little exists in forensic literature in order to interpret the significance of cranial base fractures. We analyzed 296 cases… read more here.
Keywords: frequency cranial; base fractures; base; vault fractures ... See more keywords
Benign Tumors of the Anterior Cranial Base.
Sign Up to like & getrecommendations! Published in 2020 at "Advances in oto-rhino-laryngology"
DOI: 10.1159/000457930
Abstract: Benign tumors of the anterior cranial base may originate from intracranial, cranial, or extracranial sites. Intracranial tumors such as meningiomas may secondarily involve the cranial base and extend into the sinuses or nasal cavity. Bony… read more here.
Keywords: anterior cranial; benign tumors; tumors anterior; base ... See more keywords
Cranial base synostosis in mice caused by upregulation of Wnt following partial inhibition of Shh
Sign Up to like & getrecommendations! Published in 2025 at "BMC Biology"
DOI: 10.1186/s12915-025-02381-x
Abstract: The cranial base develops from multipotent mesenchymal cells through endochondral ossification. Genetic ablation of Sonic hedgehog (Shh) or Smoothened (Smo) leads to early apoptosis of cranial base cells, thus limiting the study of their role… read more here.
Keywords: mice; wnt; shh; cranial base ... See more keywords
Clinical Grading System, Surgical Outcomes and Prognostic Analysis of Cranial Base Chordomas
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Korean Neurosurgical Society"
DOI: 10.3340/jkns.2021.0240
Abstract: Objective Cranial base chordomas are rare, but their treatment is challenging. Tumor recurrence is still common despite improvements in microsurgical techniques and postoperative radiotherapy. We retrospectively analyzed the course of treatment, overall survival, and recurrence/progression… read more here.
Keywords: survival; recurrence; grading system; base chordomas ... See more keywords
PRICKLE1 × FOCAD Interaction Revealed by Genome-Wide vQTL Analysis of Human Facial Traits
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2021.674642
Abstract: The human face is a highly complex and variable structure resulting from the intricate coordination of numerous genetic and non-genetic factors. Hundreds of genomic loci impacting quantitative facial features have been identified. While these associations… read more here.
Keywords: genome wide; focad interaction; analysis; interaction ... See more keywords