Mechanical dissection and culture of mouse cranial neural crest cells
Sign Up to like & getrecommendations! Published in 2023 at "Birth Defects Research"
DOI: 10.1002/bdr2.2148
Abstract: Owing to the contribution of cranial neural crest cells (CNCCs) to the majority of craniofacial structures, they have been studied extensively for the pathogenesis of craniofacial diseases. To investigate and summarize how to isolate and… read more here.
Keywords: culture; mouse cranial; neural crest; crest cells ... See more keywords
Cadherins function during the collective cell migration of Xenopus Cranial Neural Crest cells: revisiting the role of E-cadherin
Sign Up to like & getrecommendations! Published in 2017 at "Mechanisms of Development"
DOI: 10.1016/j.mod.2017.04.006
Abstract: Collective cell migration is a process whereby cells move while keeping contact with other cells. The Xenopus Cranial Neural Crest (CNC) is a population of cells that emerge during early embryogenesis and undergo extensive migration… read more here.
Keywords: cell migration; collective cell; migration; cranial neural ... See more keywords
Physiological electric fields induce directional migration of mammalian cranial neural crest cells.
Sign Up to like & getrecommendations! Published in 2020 at "Developmental biology"
DOI: 10.1016/j.ydbio.2020.12.011
Abstract: During neurulation, cranial neural crest cells (CNCCs) migrate long distances from the neural tube to their terminal site of differentiation. The pathway traveled by the CNCCs defines the blueprint for craniofacial construction, abnormalities of which… read more here.
Keywords: electric fields; migration; neural crest; crest cells ... See more keywords
MAPRE2 mutations result in altered human cranial neural crest migration, underlying craniofacial malformations in CSC-KT syndrome.
Sign Up to like & getrecommendations! Published in 2021 at "Scientific reports"
DOI: 10.1038/s41598-021-83771-3
Abstract: Circumferential skin creases (CSC-KT) is a rare polymalformative syndrome characterised by intellectual disability associated with skin creases on the limbs, and very characteristic craniofacial malformations. Previously, heterozygous and homozygous mutations in MAPRE2 were found to… read more here.
Keywords: mapre2; crest migration; neural crest; cranial neural ... See more keywords
hReg-CNCC reconstructs a regulatory network in human cranial neural crest cells and annotates variants in a developmental context
Sign Up to like & getrecommendations! Published in 2021 at "Communications Biology"
DOI: 10.1038/s42003-021-01970-0
Abstract: Cranial Neural Crest Cells (CNCC) originate at the cephalic region from forebrain, midbrain and hindbrain, migrate into the developing craniofacial region, and subsequently differentiate into multiple cell types. The entire specification, delamination, migration, and differentiation… read more here.
Keywords: network; hreg cncc; cncc; neural crest ... See more keywords
Post-transcriptional regulation in cranial neural crest cells expands developmental potential
Sign Up to like & getrecommendations! Published in 2023 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2212578120
Abstract: Significance Craniofacial birth defects are one of the most common congenital malformations in humans and are caused by defects in neural crest cells. In early vertebrate development, cranial neural crest cells acquire the ability to… read more here.
Keywords: neural crest; crest cells; regulation; crest ... See more keywords
Pbx loss in cranial neural crest, unlike in epithelium, results in cleft palate only and a broader midface
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Anatomy"
DOI: 10.1111/joa.12821
Abstract: Orofacial clefting represents the most common craniofacial birth defect. Cleft lip with or without cleft palate (CL/P) is genetically distinct from cleft palate only (CPO). Numerous transcription factors (TFs) regulate normal development of the midface,… read more here.
Keywords: loss cranial; cleft palate; neural crest; cranial neural ... See more keywords
Cardiac, mandibular and thymic phenotypical association indicates that cranial neural crest underlies bicuspid aortic valve formation in hamsters
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0183556
Abstract: Bicuspid aortic valve (BAV) is the most prevalent human congenital cardiac malformation. It may appear isolated, associated with other cardiovascular malformations, or forming part of syndromes. Cranial neural crest (NC) defects are supposed to be… read more here.
Keywords: isolated bav; aortic valve; bicuspid aortic; cranial neural ... See more keywords
The ectodomain of cadherin-11 binds to erbB2 and stimulates Akt phosphorylation to promote cranial neural crest cell migration
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0188963
Abstract: During development, a multi-potent group of cells known as the cranial neural crest (CNC) migrate to form craniofacial structures. Proper migration of these cells requires proteolysis of cell adhesion molecules, such as cadherins. In Xenopus… read more here.
Keywords: cnc migration; akt phosphorylation; migration; cranial neural ... See more keywords
Sonic hedgehog signaling directs patterned cell remodeling during cranial neural tube closure
Sign Up to like & getrecommendations! Published in 2020 at "eLife"
DOI: 10.7554/elife.60234
Abstract: Neural tube closure defects are a major cause of infant mortality, with exencephaly accounting for nearly one-third of cases. However, the mechanisms of cranial neural tube closure are not well understood. Here, we show that… read more here.
Keywords: neural tube; tube closure; cranial neural; apical constriction ... See more keywords