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Published in 2018 at "Developmental Dynamics"
DOI: 10.1002/dvdy.24605
Abstract: Background: The phosphatase and tensin homolog deleted on chromosome TEN (Pten) is implicated in a broad range of developmental events and diseases. However, its role in neural crest and craniofacial development has not been well…
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Keywords:
craniofacial development;
proliferation differentiation;
crest;
neural crest ... See more keywords
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Published in 2023 at "Genesis"
DOI: 10.1002/dvg.23516
Abstract: Craniofacial development is a complex process involving diverse cell populations. Various transgenic Cre lines have been developed to facilitate studying gene function in specific tissues. In this study, we have characterized the expression pattern of…
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Keywords:
pattern six2cre;
development;
craniofacial development;
expression pattern ... See more keywords
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Published in 2021 at "Head and Neck Pathology"
DOI: 10.1007/s12105-021-01301-z
Abstract: Craniofacial development, one of the most complex sequences of developmental events in embryology, features a uniquely transient, pluripotent stem cell-like population known as the neural crest (NC). Neural crest cells (NCCs) originate from the dorsal…
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Keywords:
craniofacial development;
differentiation;
embryology;
neural crest ... See more keywords
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Published in 2018 at "Journal of Dental Research"
DOI: 10.1177/0022034517732538
Abstract: A broad spectrum of human diseases called ciliopathies is caused by defective primary cilia morphology or signal transduction. The primary cilium is a solitary organelle that responds to mechanical and chemical stimuli from extracellular and…
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Keywords:
craniofacial development;
protein;
expression;
tmem107 ... See more keywords
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Published in 2022 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2022.962040
Abstract: Major organs and tissues require close association with the vasculature during development and for later function. Blood vessels are essential for efficient gas exchange and for providing metabolic sustenance to individual cells, with endothelial cells…
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Keywords:
development populating;
endothelial cells;
development;
populating patterning ... See more keywords
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Published in 2021 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.595744
Abstract: Enhancers that are conserved deep in evolutionary time regulate characteristics held in common across taxonomic classes. Here, deletion of the highly conserved Shh enhancer SBE2 (Shh brain enhancer 2) in mouse markedly reduced Shh expression…
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Keywords:
craniofacial development;
conserved shh;
expression;
highly conserved ... See more keywords
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Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.1033843
Abstract: The Notch pathway is a cell-cell communication system which is critical for many developmental processes, including craniofacial development. Notch receptor activation induces expression of several well-known canonical targets including those encoded by the hes and…
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Keywords:
craniofacial patterning;
craniofacial development;
mineralization;
distinct redundant ... See more keywords
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Published in 2020 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2020.01099
Abstract: Alternative splicing acts as a fundamental mechanism to increase the number of functional transcripts that can be derived from the genome – and its appropriate regulation is required to direct normal development, differentiation, and physiology,…
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Keywords:
craniofacial development;
program;
physiology;
alternative splicing ... See more keywords
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Published in 2022 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2022.819619
Abstract: Craniofacial development involves the regulation of a compendium of transcription factors, signaling molecules, and epigenetic regulators. Histone deacetylases (HDACs) are involved in the regulation of cell proliferation, differentiation, and homeostasis across a wide range of…
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Keywords:
development;
derived osteoblasts;
craniofacial development;
hdac4 ... See more keywords
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Published in 2023 at "Genes"
DOI: 10.3390/genes14020380
Abstract: The precise control of neural crest stem cell delamination, migration and differentiation ensures proper craniofacial and head development. Sox2 shapes the ontogeny of the cranial neural crest to ensure precision of the cell flow in…
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Keywords:
development;
fine tuned;
development fine;
craniofacial development ... See more keywords
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Published in 2022 at "Toxics"
DOI: 10.3390/toxics10100612
Abstract: Cigarette smoking remains the leading cause of preventable death and morbidity worldwide. Smoking during pregnancy is associated with numerous adverse birth outcomes, including craniofacial and behavioral abnormalities. Although tobacco smoke contains more than 4000 toxic…
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Keywords:
nicotine exposure;
embryonic nicotine;
social behavior;
craniofacial development ... See more keywords