Pten regulates neural crest proliferation and differentiation during mouse craniofacial development
Sign Up to like & getrecommendations! Published in 2018 at "Developmental Dynamics"
DOI: 10.1002/dvdy.24605
Abstract: Background: The phosphatase and tensin homolog deleted on chromosome TEN (Pten) is implicated in a broad range of developmental events and diseases. However, its role in neural crest and craniofacial development has not been well… read more here.
Keywords: craniofacial development; proliferation differentiation; crest; neural crest ... See more keywords
Expression analysis of genes including Zfhx4 in mice and zebrafish reveals a temporospatial conserved molecular basis underlying craniofacial development
Sign Up to like & getrecommendations! Published in 2024 at "Developmental Dynamics"
DOI: 10.1002/dvdy.740
Abstract: Embryonic craniofacial development involves several cellular and molecular events that are evolutionarily conserved among vertebrates. Vertebrate models such as mice and zebrafish have been used to investigate the molecular and cellular etiologies underlying human craniofacial… read more here.
Keywords: analysis genes; expression analysis; mice zebrafish; craniofacial development ... See more keywords
Characterizing expression pattern of Six2Cre during mouse craniofacial development.
Sign Up to like & getrecommendations! Published in 2023 at "Genesis"
DOI: 10.1002/dvg.23516
Abstract: Craniofacial development is a complex process involving diverse cell populations. Various transgenic Cre lines have been developed to facilitate studying gene function in specific tissues. In this study, we have characterized the expression pattern of… read more here.
Keywords: pattern six2cre; development; craniofacial development; expression pattern ... See more keywords
Craniofacial Development: Neural Crest in Molecular Embryology
Sign Up to like & getrecommendations! Published in 2021 at "Head and Neck Pathology"
DOI: 10.1007/s12105-021-01301-z
Abstract: Craniofacial development, one of the most complex sequences of developmental events in embryology, features a uniquely transient, pluripotent stem cell-like population known as the neural crest (NC). Neural crest cells (NCCs) originate from the dorsal… read more here.
Keywords: craniofacial development; differentiation; embryology; neural crest ... See more keywords
Ciliopathy Protein Tmem107 Plays Multiple Roles in Craniofacial Development
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Dental Research"
DOI: 10.1177/0022034517732538
Abstract: A broad spectrum of human diseases called ciliopathies is caused by defective primary cilia morphology or signal transduction. The primary cilium is a solitary organelle that responds to mechanical and chemical stimuli from extracellular and… read more here.
Keywords: craniofacial development; protein; expression; tmem107 ... See more keywords
Computational Methods for Image Analysis in Craniofacial Development and Disease
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Dental Research"
DOI: 10.1177/00220345241265048
Abstract: Observation is at the center of all biological sciences. Advances in imaging technologies are therefore essential to derive novel biological insights to better understand the complex workings of living systems. Recent high-throughput sequencing and imaging… read more here.
Keywords: disease; computational methods; image; analysis ... See more keywords
Exposure to maternal nicotine in utero and/or via lactation alters craniofacial development in mice
Sign Up to like & getrecommendations! Published in 2025 at "PLOS One"
DOI: 10.1371/journal.pone.0329403
Abstract: The Center for Disease Control’s National Birth Defects Prevention Study data suggests that maternal nicotine use may increase the incidence of craniofacial birth defects and growth anomalies like craniosynostosis, cleft palate, and/or lip in offspring.… read more here.
Keywords: maternal nicotine; nicotine; lactation; craniofacial development ... See more keywords
Endothelial cells during craniofacial development: Populating and patterning the head
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2022.962040
Abstract: Major organs and tissues require close association with the vasculature during development and for later function. Blood vessels are essential for efficient gas exchange and for providing metabolic sustenance to individual cells, with endothelial cells… read more here.
Keywords: development populating; endothelial cells; development; populating patterning ... See more keywords
A Highly Conserved Shh Enhancer Coordinates Hypothalamic and Craniofacial Development
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.595744
Abstract: Enhancers that are conserved deep in evolutionary time regulate characteristics held in common across taxonomic classes. Here, deletion of the highly conserved Shh enhancer SBE2 (Shh brain enhancer 2) in mouse markedly reduced Shh expression… read more here.
Keywords: craniofacial development; conserved shh; expression; highly conserved ... See more keywords
Transforming growth factor beta signaling and craniofacial development: modeling human diseases in zebrafish
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2024.1338070
Abstract: Humans and other jawed vertebrates rely heavily on their craniofacial skeleton for eating, breathing, and communicating. As such, it is vital that the elements of the craniofacial skeleton develop properly during embryogenesis to ensure a… read more here.
Keywords: biology; growth factor; transforming growth; factor beta ... See more keywords
p75 neurotrophin receptor regulates craniofacial growth and morphology in postnatal development
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2025.1569533
Abstract: Craniofacial abnormalities are among the most prevalent congenital defects, significantly affecting appearance, function, and quality of life. While the role of genetic mutations in craniofacial malformations is recognized, the underlying molecular mechanisms remain poorly understood.… read more here.
Keywords: p75 neurotrophin; neurotrophin receptor; p75ntr; growth ... See more keywords