A craniofacial-specific monosynaptic circuit enables heightened affective pain
Sign Up to like & getrecommendations! Published in 2017 at "Nature neuroscience"
DOI: 10.1038/s41593-017-0012-1
Abstract: Humans often rank craniofacial pain as more severe than body pain. Evidence suggests that a stimulus of the same intensity induces stronger pain in the face than in the body. However, the underlying neural circuitry… read more here.
Keywords: monosynaptic circuit; affective pain; specific monosynaptic; craniofacial specific ... See more keywords
Integration of 3D genome topology and local chromatin features uncovers enhancers underlying craniofacial-specific cartilage defects
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1126/sciadv.abo3648
Abstract: Aberrations in tissue-specific enhancers underlie many developmental defects. Disrupting a noncoding region distal from the human SOX9 gene causes the Pierre Robin sequence (PRS) characterized by the undersized lower jaw. Such a craniofacial-specific defect has… read more here.
Keywords: topology; cartilage; craniofacial specific; genome topology ... See more keywords