Craspase is a CRISPR RNA-guided, RNA-activated protease
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DOI: 10.1126/science.add5064
Abstract: The CRISPR-Cas type III-E RNA-targeting effector complex gRAMP/Cas7-11 is associated with a caspase-like protein (TPR-CHAT/Csx29) to form Craspase (CRISPR-guided caspase). Here, we use cryo–electron microscopy snapshots of Craspase to explain its target RNA cleavage and… read more here.
Keywords: protease; crispr; craspase; rna ... See more keywords