Developments of CRBN-based PROTACs as potential therapeutic agents.
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DOI: 10.1016/j.ejmech.2021.113749
Abstract: Protease-targeted chimeras (PROTACs) are a new technology that is receiving much attention in the treatment of diseases. The mechanism is to inhibit protein function by hijacking the ubiquitin E3 ligase for protein degradation. Heterogeneous bifunctional… read more here.
Keywords: based protacs; crbn based; developments crbn; protacs potential ... See more keywords