Articles with "crbn negative" as a keyword



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CRBN Is a Negative Regulator of Bactericidal Activity and Autophagy Activation Through Inhibiting the Ubiquitination of ECSIT and BECN1

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Published in 2019 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2019.02203

Abstract: Cereblon (CRBN) as a multifunctional protein has been extensively studied. Here, we show that CRBN is a negative regulator of bactericidal activity and autophagy activation. Mitochondrial localization of CRBN was significantly increased in response to… read more here.

Keywords: negative regulator; regulator bactericidal; autophagy activation; bactericidal activity ... See more keywords