Mechanical and Cutting Characteristics of Cobalt-Rich Ferromanganese Crusts
Sign Up to like & getrecommendations! Published in 2020 at "Rock Mechanics and Rock Engineering"
DOI: 10.1007/s00603-020-02071-w
Abstract: Hydrogenetic cobalt-rich ferromanganese crusts (cobalt-rich crusts, CRCs) are expected as potential mineral deposits for rare earth elements and platinum group elements as well as cobalt, nickel, and manganese (Manheim 1986; Rona 2003). Previous investigations have… read more here.
Keywords: strength; crcs; rich ferromanganese; ferromanganese crusts ... See more keywords
Current Microsatellite Instability Testing in Management of Colorectal Cancer.
Sign Up to like & getrecommendations! Published in 2020 at "Clinical colorectal cancer"
DOI: 10.1016/j.clcc.2020.08.001
Abstract: Colorectal cancer (CRC) is the third most common cancer worldwide. In the past decade, mismatch repair deficiency (dMMR), manifested as microsatellite instability-high (MSI-H), has been recognized as a distinct mechanism promoting tumorigenesis in 15% of… read more here.
Keywords: management; msi crcs; colorectal cancer; crcs ... See more keywords
The coding microsatellite mutation profile of PMS2-deficient colorectal cancer.
Sign Up to like & getrecommendations! Published in 2021 at "Experimental and molecular pathology"
DOI: 10.1016/j.yexmp.2021.104668
Abstract: Lynch syndrome (LS) is caused by a pathogenic heterozygous germline variant in one of the DNA mismatch repair (MMR) genes: MLH1, MSH2, MSH6 or PMS2. LS-associated colorectal carcinomas (CRCs) are characterized by MMR deficiency and… read more here.
Keywords: variant carriers; pms2; crcs; pms2 deficient ... See more keywords
Mass screening for colorectal cancer in a population of two million older adults in Guangzhou, China
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-46670-2
Abstract: Screening is an effective measure to prevent and control colorectal cancer (CRC). A mass CRC screening programme was conducted in Guangzhou from 2015 to 2017. Public media and reminders from a mobile short message service… read more here.
Keywords: crcs; colorectal cancer; mass; hrfqs ... See more keywords
RAS/RAF mutations and microsatellite instability status in primary colorectal cancers according to HER2 amplification
Sign Up to like & getrecommendations! Published in 2024 at "Scientific Reports"
DOI: 10.1038/s41598-024-62096-x
Abstract: HER2 amplification-associated molecular alterations and clinicopathologic features in colorectal cancers (CRCs) have not been well established. In this study, we assessed the prevalence of HER2 amplification and microsatellite instability (MSI) status of 992 patients with… read more here.
Keywords: her2 amplification; crcs; status; amplification ... See more keywords
Use of Colorectal Cancer Screening Among People With Mobility Disability
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Gastroenterology"
DOI: 10.1097/mcg.0000000000000835
Abstract: Goals: We aimed to assess use of colorectal cancer screening (CRCS) as per United States Preventive Task Force guidelines among people with mobility disability using a nationally representative data set. Background: Individuals with mobility disability… read more here.
Keywords: mobility disability; crcs; disability; among people ... See more keywords
Clinicopathological features and phenotypic classification of de novo‐type colorectal carcinomas differ from those of colorectal carcinomas derived from flat adenomas
Sign Up to like & getrecommendations! Published in 2019 at "Pathology International"
DOI: 10.1111/pin.12803
Abstract: Since adenoma components disappear with tumor progression, it is not known whether colorectal carcinomas (CRCs) are derived from an adenoma–carcinoma sequence or are de novo. We compared 38 cases of ≤10‐mm flat CRCs without an… read more here.
Keywords: type; crcs; colorectal carcinomas; novo type ... See more keywords
Abstract 5397: Characteristics of cancer associated fibroblasts isolated from refractory colorectal cancer using RNA sequence
Sign Up to like & getrecommendations! Published in 2024 at "Cancer Research"
DOI: 10.1158/1538-7445.am2024-5397
Abstract: Primary tumor location of colorectal cancers (CRCs) is emerging as an important prognostic factor owing to distinct biological features. In fact, the patients with right-side CRCs (R-CRCs), in which primary tumors were resected in our… read more here.
Keywords: cancer; nom value; associated fibroblasts; crcs ... See more keywords
Analysis of factors influencing molecular testing at diagnostic of colorectal cancer
Sign Up to like & getrecommendations! Published in 2017 at "BMC Cancer"
DOI: 10.1186/s12885-017-3759-6
Abstract: BackgroundThe aim of the study was to evaluate the current rate of molecular testing prescription (KRAS codons 12/13, BRAF and microsatellite instability (MSI)) in newly diagnosed colorectal cancer (CRC) patients and to determine which factors… read more here.
Keywords: factors influencing; crcs; molecular testing; colorectal cancer ... See more keywords
Comparison of phosphoproteomic profiles in left- and right-sided colorectal cancers.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2019.37.4_suppl.582
Abstract: 582 Background: Left- and right-sided colorectal cancers (CRCs) are different in terms of prognosis, treatment response and underlying molecular mechanisms. The aim of this study was to unravel the phosphoproteomic profiles of left- and right-sided… read more here.
Keywords: left right; sided colorectal; right sided; crcs ... See more keywords
BRCA2, EGFR, and NTRK mutations in mismatch repair-deficient colorectal cancers with MSH2 or MLH1 mutations
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.18098
Abstract: Deficient mismatch repair (MMR) and microsatellite instability (MSI) contribute to ~15% of colorectal cancer (CRCs). We hypothesized MSI leads to mutations in DNA repair proteins including BRCA2 and cancer drivers including EGFR. We analyzed mutations… read more here.
Keywords: mismatch repair; crcs; msh2 mlh1; mlh1 mutant ... See more keywords