Articles with "cre" as a keyword



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Heterogeneity and genomic loci of ubiquitous transgenic Cre reporter lines in zebrafish

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Published in 2022 at "Developmental Dynamics"

DOI: 10.1002/dvdy.499

Abstract: The most‐common strategy for zebrafish Cre/lox‐mediated lineage labeling experiments combines ubiquitously expressed, lox‐based Switch reporter transgenes with tissue‐specific Cre or 4‐OH‐Tamoxifen‐inducible CreERT2 driver lines. Although numerous Cre driver lines have been produced, only a few… read more here.

Keywords: reporter lines; cre; reporter; heterogeneity genomic ... See more keywords
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A novel mouse Cre‐driver line targeting Perilipin 2‐expressing cells in the neonatal lung

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Published in 2017 at "genesis"

DOI: 10.1002/dvg.23080

Abstract: Pulmonary diseases such as chronic obstructive pulmonary disease, lung fibrosis, and bronchopulmonary dysplasia are characterized by the destruction or malformation of the alveolar regions of the lung. The underlying pathomechanisms at play are an area… read more here.

Keywords: driver line; mouse cre; cre; cre driver ... See more keywords
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mTOR Signaling in X/A‐Like Cells Contributes to Lipid Homeostasis in Mice

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Published in 2019 at "Hepatology"

DOI: 10.1002/hep.30229

Abstract: Gastric mechanistic target of rapamycin (mTOR) signaling is inversely associated with the expression and secretion of ghrelin, a 28‐aa peptide hormone produced by gastric X/A‐like cells. Ghrelin contributes to obesity and hepatic steatosis. We sought… read more here.

Keywords: like cells; mtor signaling; mtor; signaling like ... See more keywords
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Establishment of a markerless multiple‐gene deletion method based on Cre/loxP mutant system for Bacillus pumilus

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Published in 2017 at "Journal of Basic Microbiology"

DOI: 10.1002/jobm.201700370

Abstract: In this study, we established a Cre/loxP mutant recombination system (Cre/lox71‐66 system) for markerless gene deletion to facilitate our follow‐up rational genetic engineering to the strain Bacillus pumilus W3. This modified method uses two mutant… read more here.

Keywords: system; loxp; cre; method ... See more keywords
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Altered baseline and amphetamine-mediated behavioral profiles in dopamine transporter Cre (DAT-Ires-Cre) mice compared to tyrosine hydroxylase Cre (TH-Cre) mice

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Published in 2020 at "Psychopharmacology"

DOI: 10.1007/s00213-020-05635-4

Abstract: Transgenic mouse lines expressing Cre-recombinase under the regulation of either dopamine transporter (DAT) or tyrosine hydroxylase (TH) promoters are commonly used to study the dopamine (DA) system. While use of the TH promoter appears to… read more here.

Keywords: cre; cre mice; dat ires; ires cre ... See more keywords
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Selectable marker recycling in the nonconventional yeast Xanthophyllomyces dendrorhous by transient expression of Cre on a genetically unstable vector

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Published in 2018 at "Applied Microbiology and Biotechnology"

DOI: 10.1007/s00253-018-9496-1

Abstract: Selectable marker recycling is a basic technique in bioengineering. However, this technique is usually unavailable in non-model microorganisms. In this study, we proposed a simple and efficient method for selectable marker recycling in the astaxanthin-synthesizing… read more here.

Keywords: vector; cre; yeast; selectable marker ... See more keywords
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Companion Animals Emerged as an Important Reservoir of Carbapenem-Resistant Enterobacteriaceae: A Report from India.

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Published in 2021 at "Current microbiology"

DOI: 10.1007/s00284-021-02355-6

Abstract: The emergence and spread of carbapenem-resistant Enterobacteriaceae (CRE) are perceived as a serious public-health threat world-wide. Despite sporadic reports, no systemic study has been carried out on CRE in companion animals in Indian subcontinent. In total,… read more here.

Keywords: carbapenem resistant; cre; companion animals; resistant enterobacteriaceae ... See more keywords
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Effective Public Health Response in Carbapenemase-Producing Carbapenem Resistant Enterobacteriaceae (CP-CRE) Outbreak in a Georgia Long Term Care Facility (LTCF), 2018

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Published in 2019 at "American Journal of Infection Control"

DOI: 10.1016/j.ajic.2019.04.073

Abstract: BACKGROUND CP-CRE are an urgent public health threat in the United States because they are associated with high morbidity/mortality, limited treatment options, and high transmissibility. In addition to providing care to a high-risk population, LTCFs… read more here.

Keywords: health; facility; infection control; public health ... See more keywords
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The YAP/TAZ transcriptional co-activators have opposing effects at different stages of osteoblast differentiation.

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Published in 2018 at "Bone"

DOI: 10.1016/j.bone.2018.04.001

Abstract: The related transcriptional co-factors YAP (Yes-associated protein) and TAZ (transcriptional co-activator with PDZ-binding motif) have been proposed to either promote or inhibit osteoblast differentiation. Here we investigated the skeletal consequences of deleting YAP and TAZ… read more here.

Keywords: yap taz; bone; cre; osteoblast differentiation ... See more keywords
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Sensitive detection of Cre-mediated recombination using droplet digital PCR reveals Tg(BGLAP-Cre) and Tg(DMP1-Cre) are active in multiple non-skeletal tissues.

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Published in 2020 at "Bone"

DOI: 10.1016/j.bone.2020.115674

Abstract: In humans, somatic activating mutations in PIK3CA are associated with skeletal overgrowth. In order to determine if activated PI3K signaling in bone cells causes overgrowth, we used Tg(BGLAP-Cre) and Tg(DMP1-Cre) mouse strains to somatically activate… read more here.

Keywords: mediated recombination; cre; dmp1 cre; cre mediated ... See more keywords
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Suppression of the coffee-ring effect by tailoring the viscosity of pharmaceutical sessile drops

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Published in 2021 at "Colloids and Surfaces A: Physicochemical and Engineering Aspects"

DOI: 10.1016/j.colsurfa.2021.126144

Abstract: Abstract The coffee ring effect (CRE) lies at the heart of droplet-based processing techniques where the drying process of the solute-laden droplet leads to the undesirable formation of a ring-like pattern with uneven distribution of… read more here.

Keywords: droplet; viscosity; ring effect; cre ... See more keywords