Neuronal GHS-R Differentially Modulates Feeding Patterns under Normal and Obesogenic Conditions
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DOI: 10.3390/biom12020293
Abstract: The orexigenic hormone ghrelin increases food intake and promotes obesity through its receptor, growth hormone secretagogue receptor (GHS-R). We previously reported two neuron-specific GHS-R knockout mouse lines, namely pan-neuronal deletion by Syn1-cre and hypothalamic deletion… read more here.
Keywords: cre; syn1 cre; mice; cre ghsrf ... See more keywords
aP2-Cre Mediated Ablation of GHS-R Attenuates Adiposity and Improves Insulin Sensitivity during Aging
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DOI: 10.3390/ijms19103002
Abstract: Ghrelin via its receptor, the growth hormone secretagogue receptor (GHS-R), increases food intake and adiposity. The tissue-specific functions of GHS-R in peripheral tissues are mostly unknown. We previously reported that while GHS-R expression is very… read more here.
Keywords: cre ghsrf; ap2 cre; ghsrf mice; mice ... See more keywords