Clinical Outcomes of Patient Subgroups in the TANGO II Study
Sign Up to like & getrecommendations! Published in 2021 at "Infectious Diseases and Therapy"
DOI: 10.1007/s40121-021-00405-x
Abstract: Meropenem–vaborbactam (M-V), a new approved antimicrobial, was developed specifically to be effective treatment for the increasingly prevalent and difficult to treat carbapenem-resistant Enterobacterales (CRE) infections. However, registration phase 3 clinical studies offer limited applicability to… read more here.
Keywords: renal failure; failure immunocompromised; immunocompromised status; tango study ... See more keywords
Optimizing therapy in carbapenem-resistant Enterobacteriaceae infections.
Sign Up to like & getrecommendations! Published in 2018 at "Current opinion in infectious diseases"
DOI: 10.1097/qco.0000000000000493
Abstract: PURPOSE OF REVIEW In the absence of randomized clinical trial data, questions remain regarding the optimal treatment of carbapenem-resistant Enterobacteriaceae (CRE) infections. CRE have historically been susceptible to polymyxins, tigecycline or aminoglycosides (mostly gentamicin), and… read more here.
Keywords: caz avi; carbapenem resistant; resistant enterobacteriaceae; therapy ... See more keywords
Risk Factors for Carbapenem-Resistant Enterobacterales Clinical Treatment Failure
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DOI: 10.1128/spectrum.02647-22
Abstract: This work compares carbapenem-resistant Enterobacterales (CRE) infections using patient, clinical, and treatment variables to understand which characteristics are associated with the highest risk of clinical failure. Knowing which risk factors are associated with CRE infection… read more here.
Keywords: carbapenem resistant; cre infections; failure; risk factors ... See more keywords
Mortality-Related Risk Factors and Novel Antimicrobial Regimens for Carbapenem-Resistant Enterobacteriaceae Infections: A Systematic Review
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DOI: 10.2147/idr.s390635
Abstract: Objective Carbapenem-resistant Enterobacteriaceae (CRE) has become a significant public health problem in the last decade. We aimed to explore the risk factors of mortality in patients with CRE infections and to focus on the current… read more here.
Keywords: related risk; cre infections; risk factors; mortality ... See more keywords