677. Activity of Novel β-Lactamase Inhibitor QPX7728 Combined with β-Lactam Agents When Tested Against Carbapenem-Resistant Enterobacteriaceae (CRE) Isolates
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DOI: 10.1093/ofid/ofz360.745
Abstract: Abstract Background CREs have been described worldwide and these isolates are often multidrug resistant with few therapeutic options remaining active against them. New β-lactam (BL)/β-lactamase inhibitor (BLI) combinations recently approved are active against KPC and… read more here.
Keywords: cre isolates; qpx; lactamase inhibitor; etp ... See more keywords
Molecular characterization of carbapenem-resistant Enterobacterales (CRE) and in vitro activity of novel beta lactams against CRE isolates from Malaysia
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DOI: 10.1128/spectrum.00553-25
Abstract: ABSTRACT Knowledge gap on the susceptibility of novel β-lactam agents (cefiderocol, ceftazidime-avibactam, imipenem-cilastatin-relebectam, and aztreonam) against carbapenem-resistant Enterobacterales (CRE) has been recognized. This study aimed to genotypically characterize CRE isolates and investigate the novel β-lactam… read more here.
Keywords: cre isolates; ceftazidime avibactam; resistant enterobacterales; cre ... See more keywords
Molecular characterization of class 1 integrons in carbapenem-resistant Enterobacterales isolates.
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DOI: 10.2139/ssrn.4267927
Abstract: OBJECTIVE Carbapenem-resistant Enterobacterales (CRE) infections result in higher treatment costs and mortality rates. Integrons play important roles in emergence and spread of antibiotic resistant genes. To get a better understand on the effects of integron… read more here.
Keywords: carbapenem resistant; class integrons; class; cre isolates ... See more keywords
Effect of Colistin, Fosfomycin and Meropenem/Vaborbactam on Carbapenem-Resistant Enterobacterales in Egypt: A Cross-Sectional Study
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DOI: 10.2147/idr.s385411
Abstract: Purpose The increasing multi-drug carbapenem resistance among Enterobacterales are a severe health problem limiting therapeutic options and worsen the prognosis. This study characterizes carbapenemase genes and integrons among uropathogenic carbapenem resistant Enterobacterales (CRE) isolates recovered… read more here.
Keywords: fosfomycin meropenem; carbapenem resistant; meropenem; cre isolates ... See more keywords
Fecal carriage and molecular characterization of carbapenem-resistant Enterobacteriaceae from hospitalized children in a tertiary hospital of Shandong, China
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DOI: 10.3389/fmicb.2025.1542207
Abstract: Background The prevalence of carbapenem-resistant Enterobacteriaceae (CRE) has emerged as a serious public health problem worldwide, and the data on the fecal carriage of CRE strains in hospitalized children remain limited. This study aimed to… read more here.
Keywords: hospitalized children; fecal carriage; resistance; cre isolates ... See more keywords