The Use of Cre/loxP Inducible Mouse Models to Dissect the Specific Roles of Calcineurin Signaling in Myeloid Cells.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9030-6_14
Abstract: The calcineurin/nuclear factor of activated T-cell (NFAT) signaling pathway is important for the development and function of different leukocyte subsets. Calcineurin is activated through increased intracellular levels of calcium that is triggered by cell receptors.… read more here.
Keywords: mouse models; inducible mouse; loxp inducible; calcineurin ... See more keywords
Genome editing of different strains of Aureobasidium melanogenum using an efficient Cre/loxp site-specific recombination system.
Sign Up to like & getrecommendations! Published in 2019 at "Fungal biology"
DOI: 10.1016/j.funbio.2019.06.001
Abstract: It has been well known that different strains of Aureobasidium spp. can produce commercial pullulan, polymalate, liamocin, intracellular lipids, gluconic acid, siderophore, melanin and various enzymes. In order to fully elucidate their synthetic pathways and… read more here.
Keywords: system; loxp site; cre loxp; site specific ... See more keywords
Viral Cre-LoxP tools aid genome engineering in mammalian cells
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Biological Engineering"
DOI: 10.1186/s13036-017-0087-y
Abstract: BackgroundTargeted nucleases have transformed genome editing technology, providing more efficient methods to make targeted changes in mammalian genome. In parallel, there is an increasing demand of Cre-LoxP technology for complex genome manipulation such as large… read more here.
Keywords: engineering; cre recombinase; cre loxp; mammalian cells ... See more keywords
Transgenic mouse model exhibiting weak red fluorescence before and strong green fluorescence after Cre/loxP-mediated recombination
Sign Up to like & getrecommendations! Published in 2020 at "Experimental Animals"
DOI: 10.1538/expanim.19-0085
Abstract: The Cre/loxP system is an indispensable tool for temporal and spatial control of gene function in mice. Many mice that express Cre and carry loxP sites in their genomes have been bred for functional analysis… read more here.
Keywords: red fluorescence; fluorescence; cre; cre loxp ... See more keywords
Cre/LoxP Genetic Recombination Sustains Cartilage Anabolic Factor Expression in Hyaluronan Encapsulated MSCs Alleviates Intervertebral Disc Degeneration
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10030555
Abstract: (1) Background: Inexplicable low back and neck pain frequently results from spinal disc degeneration with an imbalanced intervertebral disc (IVD) cell homeostasis. We hypothesize that introducing MSC expressing a sustained cartilage-anabolic factor in the IVD… read more here.
Keywords: anabolic factor; disc degeneration; cre loxp; cartilage anabolic ... See more keywords