Altered baseline and amphetamine-mediated behavioral profiles in dopamine transporter Cre (DAT-Ires-Cre) mice compared to tyrosine hydroxylase Cre (TH-Cre) mice
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DOI: 10.1007/s00213-020-05635-4
Abstract: Transgenic mouse lines expressing Cre-recombinase under the regulation of either dopamine transporter (DAT) or tyrosine hydroxylase (TH) promoters are commonly used to study the dopamine (DA) system. While use of the TH promoter appears to… read more here.
Keywords: cre; cre mice; dat ires; ires cre ... See more keywords
Preserved dopaminergic homeostasis and dopamine‐related behaviour in hemizygous TH‐Cre mice
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DOI: 10.1111/ejn.13347
Abstract: Cre‐driver mouse lines have been extensively used as genetic tools to target and manipulate genetically defined neuronal populations by expression of Cre recombinase under selected gene promoters. This approach has greatly advanced neuroscience but interpretations… read more here.
Keywords: dopamine; preserved dopaminergic; dopaminergic homeostasis; cre mice ... See more keywords
Abstract 137: Impact of Leptin Deficiency Compared to Neuronal Specific Leptin Receptor Deletion on Cardiometabolic Regulation
Sign Up to like & getrecommendations! Published in 2019 at "Hypertension"
DOI: 10.1161/hyp.74.suppl_1.137
Abstract: The main goal of this study was to compare the impact of whole-body leptin deficiency with neuronal specific leptin receptor (LR) deletion on metabolic and cardiovascular regulation. Liver fat, diacylglycerol acyltransferase-2 (DGTA2) and CD36 protein… read more here.
Keywords: nestin cre; cre mice; mice; leptin deficiency ... See more keywords
Reduced VIP Expression Affects Circadian Clock Function in VIP-IRES-CRE Mice (JAX 010908)
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DOI: 10.1177/0748730420925573
Abstract: Circadian rhythms are programmed by the suprachiasmatic nucleus (SCN), which relies on neuropeptide signaling to maintain daily timekeeping. Vasoactive intestinal polypeptide (VIP) is critical for SCN function, but the precise role of VIP neurons in… read more here.
Keywords: vip; ires cre; vip expression; vip ires ... See more keywords
Type I interferon signaling attenuates regulatory T cell function in viral infection and in the tumor microenvironment
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DOI: 10.1371/journal.ppat.1006985
Abstract: Regulatory T cells (Tregs) play a cardinal role in the immune system by suppressing detrimental autoimmune responses, but their role in acute, chronic infectious diseases and tumor microenvironment remains unclear. We recently demonstrated that IFN-α/β… read more here.
Keywords: flxfoxp3yfp cre; infection; cre mice; ifnarfl flxfoxp3yfp ... See more keywords
Dissociable effects of oxycodone on behavior, calcium transient activity, and excitability of dorsolateral striatal neurons
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Neural Circuits"
DOI: 10.3389/fncir.2022.983323
Abstract: Opioids are the most common medications for moderate to severe pain. Unfortunately, they also have addictive properties that have precipitated opioid misuse and the opioid epidemic. In the present study, we examined the effects of… read more here.
Keywords: cre; effects oxycodone; activity; cre mice ... See more keywords