Replacement of the carbon catabolite regulator (cre1) and fed-batch cultivation as strategies to enhance cellulase production in Trichoderma harzianum
Sign Up to like & getrecommendations! Published in 2021 at "Bioresource Technology Reports"
DOI: 10.1016/j.biteb.2021.100634
Abstract: Abstract This work focused on mitigating carbon catabolic repression (CCR) and increasing cellulase production in Trichoderma harzianum based on the cre1 deletion. The CRE1 protein (encoded by cre1) has been described as a cellulase transcriptional… read more here.
Keywords: production trichoderma; cre1; cellulase production; carbon ... See more keywords
Precision Engineering of the Transcription Factor Cre1 in Hypocrea jecorina (Trichoderma reesei) for Efficient Cellulase Production in the Presence of Glucose
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2020.00852
Abstract: In Trichoderma reesei, carbon catabolite repression (CCR) significantly downregulates the transcription of cellulolytic enzymes, which is usually mediated by the zinc finger protein Cre1. It was found that there is a conserved region at the… read more here.
Keywords: transcription; production; precision engineering; cre1 ... See more keywords