Characterization of a functional recombinant human creatine kinase-MB isoenzyme prepared by tandem affinity purification from Escherichia coli
Sign Up to like & getrecommendations! Published in 2017 at "Applied Microbiology and Biotechnology"
DOI: 10.1007/s00253-017-8286-5
Abstract: Creatine kinase isoform CK-MB has been widely applied as a biomarker of myocardial injury. While a variety of methods have been used to measure CK-MB activity or mass in clinical laboratories, a CK-MB standard is… read more here.
Keywords: creatine; tandem affinity; human creatine; affinity purification ... See more keywords
Elevated serum creatine kinase in the early stage of sporadic amyotrophic lateral sclerosis
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DOI: 10.1007/s00415-019-09507-6
Abstract: To assess the changes of muscle-related biomarkers at the early stage of amyotrophic lateral sclerosis, and to confirm these findings in an experimental animal model. Thirty-nine subjects with sporadic amyotrophic lateral sclerosis and 20 healthy… read more here.
Keywords: sporadic amyotrophic; amyotrophic lateral; early stage; creatine kinase ... See more keywords
Structure and function of resistance arteries from BB-creatine kinase and ubiquitous Mt-creatine kinase double knockout mice
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DOI: 10.1007/s00726-020-02872-x
Abstract: Increasing evidence indicates that the enzyme creatine kinase (CK) is intimately involved in microvascular contractility. The mitochondrial isoenzyme catalyses phosphocreatine synthesis from ATP, while cytoplasmic CK, predominantly the BB isoenzyme in vascular tissue, is tightly… read more here.
Keywords: resistance arteries; function; kinase; creatine kinase ... See more keywords
Early postictal serum lactate concentrations are superior to serum creatine kinase concentrations in distinguishing generalized tonic–clonic seizures from syncopes
Sign Up to like & getrecommendations! Published in 2017 at "Internal and Emergency Medicine"
DOI: 10.1007/s11739-017-1745-2
Abstract: Concentrations of serum creatine kinase (CK) and serum lactate are frequently measured to help differentiate between generalized tonic–clonic seizures (GTCS) and syncope. The aim of this prospective cohort study was to systematically compare these two… read more here.
Keywords: syncope; serum creatine; lactate; creatine kinase ... See more keywords
Creatine kinase/α-crystallin interaction functions in cataract development
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DOI: 10.1016/j.bbrep.2020.100748
Abstract: Creatine kinase (CK) is an energy storage enzyme that plays an important role in energy metabolism. CK/phosphocreatine functions as an energy buffer and links ATP production sites with ATP utilization sites. Several key mutations in… read more here.
Keywords: interaction; interaction crystallin; cataract development; creatine kinase ... See more keywords
Comparative studies of the expression of creatine kinase isoforms under immune stress in Pelodiscus sinensis
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Biological Macromolecules"
DOI: 10.1016/j.ijbiomac.2020.06.036
Abstract: Abstract The expression and localization of different isoforms of creatine kinase in Pelodiscus sinensis (PSCK) were studied to reveal the role of PSCK isozymes (PSCK-B, PSCK-M, PSCK-S) under bacterial infection-induced immunologic stress. The computational molecular… read more here.
Keywords: pelodiscus sinensis; kinase; psck isozymes; psck ... See more keywords
Elevated creatine kinase levels, exercise, and isotretinoin for acne
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DOI: 10.1016/j.jdcr.2021.07.044
Abstract: CK: creatine kinase INTRODUCTION Approximately 44% of patients on isotretinoin develop elevated levels of creatine kinase (CK), a proxy for potential muscle tissue damage. Mild elevations are typically transient and well-tolerated, whereas marked elevations can… read more here.
Keywords: elevated creatine; kinase levels; kinase; levels exercise ... See more keywords
Creatine kinase pathway inhibition alters GSK3 and WNT signaling in EVI1-positive AML
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DOI: 10.1038/s41375-018-0291-x
Abstract: Over the past decade, several inhibitors of key metabolic dependencies have been shown to be active in AML (Acute Myeloid Leukemia), suggesting that targeting cellular metabolism is a promising therapeutic strategy for this disease. Specific… read more here.
Keywords: creatine; evi1 positive; inhibition; positive aml ... See more keywords
Interrelationship of rotavirus infection and Creatine Kinase-MB isoenzyme levels in children hospitalized with acute gastroenteritis in Guangzhou, China, 2012–2015
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DOI: 10.1038/s41598-017-07636-4
Abstract: Elevated levels of Creatine Kinase-MB (CK-MB) Isoenzyme are a common phenomenon among rotavirus (RV) diarrhea. However, few studies have addressed this issue using large sample size. In current study, 1,118 children (age read more here.
Keywords: 2012 2015; infection; kinase isoenzyme; creatine kinase ... See more keywords
The creatine kinase system as a therapeutic target for myocardial ischaemia–reperfusion injury
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DOI: 10.1042/bst20170504
Abstract: Restoring blood flow following an acute myocardial infarction saves lives, but results in tissue damage due to ischaemia–reperfusion injury (I/R). Ameliorating this damage is a major research goal to improve recovery and reduce subsequent morbidity… read more here.
Keywords: system; reperfusion; ischaemia reperfusion; creatine kinase ... See more keywords
Massively elevated creatine kinase levels in antihistamine-induced rhabdomyolysis
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DOI: 10.1080/08998280.2019.1688624
Abstract: Abstract Rhabdomyolysis is the destruction of skeletal muscle tissue with release of intracellular components into the circulation. Elevation of creatine kinase levels in serum is indicative of muscle damage and is associated with acute kidney… read more here.
Keywords: elevated creatine; rhabdomyolysis; massively elevated; creatine kinase ... See more keywords