Articles with "creating mhc" as a keyword



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Creating MHC-Restricted Neoantigens with Covalent Inhibitors That Can Be Targeted by Immune Therapy

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Published in 2022 at "Cancer Discovery"

DOI: 10.1158/2159-8290.cd-22-1074

Abstract: Cancer-specific neoantigens created in the form of a covalent drug conjugated to a fragment of an intracellular oncoprotein selectively mark drug-resistant cancer cells for killing with bispecific T-cell engagers. read more here.

Keywords: inhibitors targeted; neoantigens covalent; covalent inhibitors; mhc restricted ... See more keywords