Articles with "creatininase" as a keyword



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Role of water coordination at zinc binding site and its catalytic pathway of dizinc creatininase: insights from quantum cluster approach

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Published in 2022 at "Journal of Computer-Aided Molecular Design"

DOI: 10.1007/s10822-022-00451-8

Abstract: Creatininase is a key enzyme of creatinine-metabolizing pathway in mammals, and has a great potential for diagnostic application. It catalyzes the reversible conversion of creatinine to creatine. Here, we investigated its reaction mechanism with density… read more here.

Keywords: role; proton; reaction; creatininase ... See more keywords