Edoxaban Exposure in Patients With Atrial Fibrillation and Estimated Creatinine Clearance Exceeding 100 mL/min.
Sign Up to like & getrecommendations! Published in 2021 at "Clinical pharmacology in drug development"
DOI: 10.1002/cpdd.1050
Abstract: Edoxaban 60 mg is approved for stroke prevention in patients with atrial fibrillation (AF) not fulfilling any dose-reduction criteria. As edoxaban is partially renally cleared (≈50%), this study compared pharmacokinetics (PK) and pharmacodynamics of edoxaban 60 mg… read more here.
Keywords: edoxaban exposure; atrial fibrillation; exposure; patients atrial ... See more keywords
Impact of age and renal function on urine chemistry in patients with calcium oxalate kidney stones
Sign Up to like & getrecommendations! Published in 2021 at "Urolithiasis"
DOI: 10.1007/s00240-021-01254-6
Abstract: Nephrolithiasis is associated with an increased risk of chronic kidney disease, and its incidence varies with age. However, little is known on the combined impact of aging and declining renal function on urinary risk factors… read more here.
Keywords: age; chemistry; creatinine clearance; calcium oxalate ... See more keywords
Assessment of direct oral anticoagulants administered as potentially inappropriate medications to elderly inpatients
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Clinical Pharmacy"
DOI: 10.1007/s11096-020-01051-y
Abstract: Background There is evidence that direct oral anticoagulants administered as potentially inappropriate medications increase the risk of bleeding and thromboembolic complications, which represent serious threats to human health. Objective To identify direct oral anticoagulants administered… read more here.
Keywords: oral anticoagulants; direct oral; creatinine clearance; inappropriate medications ... See more keywords
Can we reliably predict the level of anticoagulation after enoxaparin injection in elderly patients with renal failure?
Sign Up to like & getrecommendations! Published in 2017 at "Aging Clinical and Experimental Research"
DOI: 10.1007/s40520-017-0822-8
Abstract: ObjectivesThe aim of this study was to evaluate the activity of anti-activated factor X (anti-Xa) in patients with different degrees of chronic renal failure (CRF), treated with therapeutic doses of low molecular weight heparin.DesignThis prospective… read more here.
Keywords: renal failure; renal function; creatinine clearance; reliably predict ... See more keywords
Cardiovascular pathologies in post-covid syndrome
Sign Up to like & getrecommendations! Published in 2023 at "European Journal of Preventive Cardiology"
DOI: 10.1093/eurjpc/zwad125.337
Abstract: Type of funding sources: None. Problems of cardiovascular system and kidney function often follows the disease of Covid-19. Our aim was revealing and evaluation of cardiovascular disorders and kidney problems in patients who recovered from… read more here.
Keywords: cardiovascular system; covid infection; creatinine clearance; pressure ... See more keywords
#326 Metabolomic profiling of urine in post-kidney transplant patients: insights into allograft function and creatinine clearance
Sign Up to like & getrecommendations! Published in 2025 at "Nephrology Dialysis Transplantation"
DOI: 10.1093/ndt/gfaf116.1809
Abstract: End-stage kidney disease is optimally managed through kidney transplantation. However, the suboptimal function of the transplanted kidney can lead to imbalances in processes controlled by the kidneys, necessitating long-term monitoring of the graft's function and… read more here.
Keywords: allograft function; function; transplant patients; creatinine clearance ... See more keywords
Relationship between creatinine clearance and clinical outcomes in Chinese emergency patients with atrial fibrillation
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Noninvasive Electrocardiology"
DOI: 10.1111/anec.12942
Abstract: Few real‐world data on the relation between creatinine clearance (CrCl) and adverse clinical outcomes in Chinese emergency department (ED) patients with nonvalvular atrial fibrillation (AF). read more here.
Keywords: clinical outcomes; creatinine clearance; outcomes chinese; chinese emergency ... See more keywords
EVALUATING PREDICTION METHODS FOR GLOMERULAR FILTRATION TO OPTIMISE DRUG DOSES IN OBESE AND NON-OBESE PATIENTS.
Sign Up to like & getrecommendations! Published in 2021 at "British journal of clinical pharmacology"
DOI: 10.1111/bcp.15115
Abstract: The most suitable method for predicting the glomerular filtration rate (GFR) in obesity is currently debated. Therefore, multiple GFR/creatinine clearance prediction methods were applied to (morbidly) obese and non-obese patients ranging from moderate renal impairment… read more here.
Keywords: obese patients; creatinine clearance; glomerular filtration; clearance ... See more keywords
Effect of intra-abdominal hypertension on plasma exogenous creatinine clearance in conscious and anesthetized dogs.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of veterinary emergency and critical care"
DOI: 10.1111/vec.12853
Abstract: OBJECTIVE To evaluate the effect of intra-abdominal pressure (IAP) on plasma exogenous creatinine clearance in both conscious and anesthetized dog models using a balloon technique to generate intra-abdominal hypertension. DESIGN Prospective, cross-over, experimental study. SETTING… read more here.
Keywords: plasma exogenous; abdominal hypertension; creatinine clearance; exogenous creatinine ... See more keywords
SGLT2 Inhibitors May Increase Creatinine Clearance: Data Mining Utilizing the FDA Adverse Event Report System Database and Pharmacokinetic Study with Rats
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DOI: 10.1159/000546838
Abstract: Abstract Introduction: Augmented renal clearance is a condition in which creatinine clearance exceeds 130 mL/min/1.73 m2. The present study aimed to identify drugs that increase creatinine clearance. Methods: We initially investigated drugs associated with an… read more here.
Keywords: renal clearance; fda adverse; clearance; increase creatinine ... See more keywords
Correlation of Measured and Estimated Creatinine Clearance in Hospitalized Elderly Patients: A Retrospective Cohort Study
Sign Up to like & getrecommendations! Published in 2020 at "Hospital Pharmacy"
DOI: 10.1177/0018578720919026
Abstract: Background: Accurate assessment of renal function is essential in hospitalized elderly patients. Few studies have examined the accuracy of Cockcroft-Gault (C-G) estimates of creatinine clearance (C... read more here.
Keywords: measured estimated; correlation measured; creatinine clearance; elderly patients ... See more keywords