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Minocycline Attenuates Lipopolysaccharide-Induced Locomotor Deficit and Anxiety-like Behavior and Related Expression of the BDNF/CREB Protein in the Rat Medial Prefrontal Cortex (mPFC)

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Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms232113474

Abstract: Neuroinflammation following lipopolysaccharide (LPS) administration induces locomotor deficits and anxiety-like behaviour. In this study, minocycline was compared to memantine, an NMDA receptor antagonist, for its effects on LPS-induced locomotor deficits and anxiety-like behaviour in rats.… read more here.

Keywords: induced locomotor; like behaviour; anxiety like; creb protein ... See more keywords