Melatonin Inhibits NF-κB/CREB/Runx2 Signaling and Alleviates Aortic Valve Calcification
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DOI: 10.3389/fcvm.2022.885293
Abstract: Calcific aortic valve disease (CAVD) is linked to high mortality. Melatonin inhibits nuclear factor-kappa B (NF-κB)/cyclic AMP response element-binding protein (CREB), contributing to CAVD progression. This study determined the role of melatonin/MT1/MT2 signaling in valvular… read more here.
Keywords: aortic valve; calcification; creb runx2; melatonin inhibits ... See more keywords