Creeping fat formation and interaction with intestinal disease in Crohn's disease
Sign Up to like & getrecommendations! Published in 2022 at "United European Gastroenterology Journal"
DOI: 10.1002/ueg2.12349
Abstract: Abstract Creeping fat (CrF), also known as fat wrapping, is a significant disease characteristic of Crohn's disease (CD). The transmural inflammation impairs intestinal integrity and facilitates bacteria translocation, aggravating immune response. CrF is a rich… read more here.
Keywords: crf; disease; crohn disease; fat formation ... See more keywords
Creeping Fat in Crohn's Disease: Innocuous or innocuum?
Sign Up to like & getrecommendations! Published in 2020 at "Immunity"
DOI: 10.1016/j.immuni.2020.10.018
Abstract: In Crohn's disease, the characteristic expansion of mesenteric tissue on sites of intestinal inflammation is known as creeping fat. In a recent issue of Cell, Ha et al. report that translocation of gut bacteria to the… read more here.
Keywords: fat crohn; creeping fat; disease innocuous; crohn disease ... See more keywords
Adipocytes orchestrate the formation of tertiary lymphoid organs in the creeping fat of Crohn's disease affected mesentery.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of autoimmunity"
DOI: 10.1016/j.jaut.2019.05.009
Abstract: The formation of tertiary lymphoid organs (TLOs) is orchestrated by the stromal cells of tissues chronically submitted to inflammatory stimuli, in order to uphold specific adaptive immune responses. We have recently shown that the smooth… read more here.
Keywords: mesentery; formation; affected mesentery; creeping fat ... See more keywords
Creeping Fat in the Pathogenesis of Crohn's Disease: An Orchestrator or a Silent Bystander?
Sign Up to like & getrecommendations! Published in 2023 at "Inflammatory bowel diseases"
DOI: 10.1093/ibd/izad095
Abstract: Although the phenomenon of hypertrophied adipose tissue surrounding inflamed bowel segments in Crohn's disease has been described since 1932, the mechanisms mediating the creeping fat formation and its role in the pathogenesis of the disease… read more here.
Keywords: disease; adipose tissue; crohn disease; creeping fat ... See more keywords
Fibrosis in fat: From other diseases to Crohn’s disease
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.935275
Abstract: Creeping fat is a specific feature of Crohn’s disease (CD) and is characterized by mesenteric fat wrapping around the intestine. It highly correlates with intestinal transmural inflammation, muscular hypertrophy, fibrosis, and stricture formation. However, the… read more here.
Keywords: fat fibrosis; crohn disease; mesenteric fat; fibrosis ... See more keywords
Crohn’s Disease Increases the Mesothelial Properties of Adipocyte Progenitors in the Creeping Fat
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22084292
Abstract: Our understanding of the interplay between human adipose tissue and the immune system is limited. The mesothelium, an immunologically active structure, emerged as a source of visceral adipose tissue. After investigating the mesothelial properties of… read more here.
Keywords: mesothelial properties; disease; creeping fat; adipose tissue ... See more keywords