CD44 is required for the pathogenesis of experimental crescentic glomerulonephritis and collapsing focal segmental glomerulosclerosis.
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DOI: 10.1016/j.kint.2017.09.020
Abstract: A key feature of glomerular diseases such as crescentic glomerulonephritis and focal segmental glomerulosclerosis is the activation, migration and proliferation of parietal epithelial cells. CD44-positive activated parietal epithelial cells have been identified in proliferative cellular… read more here.
Keywords: focal segmental; crescentic glomerulonephritis; parietal epithelial; segmental glomerulosclerosis ... See more keywords
Activation of fibroblastic reticular cells in kidney lymph node during crescentic glomerulonephritis.
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DOI: 10.1016/j.kint.2018.08.040
Abstract: Crescentic glomerulonephritis is an inflammatory condition characterized by rapid deterioration of kidney function. Previous studies of crescentic glomerulonephritis have focused on immune activation in the kidney. However, the role of fibroblastic reticular cells, which reside… read more here.
Keywords: kidney lymph; crescentic glomerulonephritis; reticular cells; fibroblastic reticular ... See more keywords
The lectin pathway does not contribute to glomerular injury in the nephrotoxic nephritis model.
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DOI: 10.1111/nep.13988
Abstract: AIMS Rapidly progressive crescentic glomerulonephritis occurs in a number systemic and primary glomerular diseases, including anti-glomerular basement membrane disease, anti-neutrophil cytoplasmic antibody vasculitis, and lupus nephritis. Our understanding of pathogenic mechanisms comes from animal models… read more here.
Keywords: nephrotoxic nephritis; lectin pathway; nephritis model; crescentic glomerulonephritis ... See more keywords
Differentiation of crescent-forming kidney progenitor cells into podocytes attenuates severe glomerulonephritis in mice
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DOI: 10.1126/scitranslmed.abg3277
Abstract: Crescentic glomerulonephritis is characterized by vascular necrosis and parietal epithelial cell hyperplasia in the space surrounding the glomerulus, resulting in the formation of crescents. Little is known about the molecular mechanisms driving this process. Inducing… read more here.
Keywords: cell; kidney; progenitor; progenitor cells ... See more keywords
Tuberculosis and pauci-immune crescentic glomerulonephritis
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DOI: 10.1136/bcr-2017-221948
Abstract: We report here a case that highlights tuberculosis (TB) as a possible cause for pauci-immune crescentic glomerulonephritis (c-GN), an important and often treatable cause of kidney injury. A 47-year-old HIV-negative man of mixed ethnicity presented… read more here.
Keywords: crescentic glomerulonephritis; tuberculosis; immune crescentic; pauci immune ... See more keywords
Crescentic glomerulonephritis: what’s different in South Asia? A single center observational cohort study
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DOI: 10.12688/wellcomeopenres.16071.1
Abstract: Background: The spectrum and outcomes of crescentic glomerulonephritis (Cr.GN) in South Asia is vastly different from that reported worldwide and there is a paucity of information. The aim of the study was to study the… read more here.
Keywords: crescentic glomerulonephritis; study; south asia; cohort ... See more keywords
Crescentic Glomerulonephritis with Fibrinoid Vasculitis after Administration of Influenza Vaccine
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DOI: 10.2169/internalmedicine.9410-22
Abstract: A 66-year-old man was admitted to our hospital because of a low-grade fever and arthralgia. The symptoms started on the third day after influenza vaccine administration and persisted for two months. Serum creatinine was 1.0… read more here.
Keywords: glomerulonephritis fibrinoid; administration; influenza vaccine; fibrinoid vasculitis ... See more keywords
Crescentic Glomerulonephritis: Pathogenesis and Therapeutic Potential of Human Amniotic Stem Cells
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DOI: 10.3389/fphys.2021.724186
Abstract: Chronic kidney disease (CKD) leads to significant morbidity and mortality worldwide. Glomerulonephritis (GN) is the second leading cause of CKD resulting in end stage renal failure. The most severe and rapidly progressive type of GN… read more here.
Keywords: glomerulonephritis pathogenesis; crescentic glomerulonephritis; human amniotic; pathogenesis therapeutic ... See more keywords
Annexin A1 exerts renoprotective effects in experimental crescentic glomerulonephritis
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DOI: 10.3389/fphys.2022.984362
Abstract: Non-resolving inflammation plays a critical role during the transition from renal injury towards end-stage renal disease. The glucocorticoid-inducible protein annexin A1 has been shown to function as key regulator in the resolution phase of inflammation,… read more here.
Keywords: gene; annexin; ontology; analysis ... See more keywords
Rare Case Report of De-novo Pauci-immune Necrotizing Crescentic Glomerulonephritis in 1st-week Post-kidney Transplantation
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DOI: 10.4103/ijn.ijn_405_19
Abstract: Early post-transplant de-novo pauci-immune necrotizing crescentic glomerulonephritis occurring within the first week post transplantation has not been reported according to the literature search done by us. Here, we are reporting a 56 years male patient… read more here.
Keywords: immune necrotizing; novo pauci; crescentic glomerulonephritis; pauci immune ... See more keywords