Regulation of Oct4 in stem cells and neural crest cells
Sign Up to like & getrecommendations! Published in 2022 at "Birth Defects Research"
DOI: 10.1002/bdr2.2007
Abstract: During embryonic development, cells gradually restrict their developmental potential as they exit pluripotency and differentiate into various cell types. The POU transcription factor Oct4 (encoded by Pou5f1) lies at the center of the pluripotency machinery… read more here.
Keywords: neural crest; regulation oct4; crest cells; stem ... See more keywords
Mechanical dissection and culture of mouse cranial neural crest cells
Sign Up to like & getrecommendations! Published in 2023 at "Birth Defects Research"
DOI: 10.1002/bdr2.2148
Abstract: Owing to the contribution of cranial neural crest cells (CNCCs) to the majority of craniofacial structures, they have been studied extensively for the pathogenesis of craniofacial diseases. To investigate and summarize how to isolate and… read more here.
Keywords: culture; mouse cranial; neural crest; crest cells ... See more keywords
Local heat‐shock mediated multi‐color labeling visualizing behaviors of enteric neural crest cells associated with division and neurogenesis in zebrafish gut
Sign Up to like & getrecommendations! Published in 2019 at "Developmental Dynamics"
DOI: 10.1002/dvdy.36
Abstract: The enteric nervous system (ENS) is derived from enteric neural crest cells (ENCCs) that migrate into the gut. The zebrafish larva is a good model to study ENCC development due to its simplicity and transparency.… read more here.
Keywords: gut; local heat; enteric neural; neural crest ... See more keywords
Filling in the phylogenetic gaps: Induction, migration, and differentiation of neural crest cells in a squamate reptile, the veiled chameleon (Chamaeleo calyptratus)
Sign Up to like & getrecommendations! Published in 2019 at "Developmental Dynamics"
DOI: 10.1002/dvdy.38
Abstract: Neural crest cells comprise a migratory progenitor cell population that differentiate into cell types such as neurons and glia of the peripheral nervous system, pigment cells, hormone secreting cells in glands, and skeletal and connective… read more here.
Keywords: filling phylogenetic; crest; neural crest; crest cells ... See more keywords
Direct Conversion of Mouse Embryonic Fibroblasts into Neural Crest Cells.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/7651_2018_145
Abstract: Neural crest cells (NCCs) are multipotent cells that emerge from the edges of the neural folds and extensively migrate throughout developing embryos. Dorsolaterally migrating NCCs colonize skin, differentiate into skin melanocytes, and lose their multipotency.… read more here.
Keywords: conversion mouse; direct conversion; biology; neural crest ... See more keywords
A structure–activity relationship linking non-planar PCBs to functional deficits of neural crest cells: new roles for connexins
Sign Up to like & getrecommendations! Published in 2017 at "Archives of Toxicology"
DOI: 10.1007/s00204-017-2125-4
Abstract: Migration of neural crest cells (NCC) is a fundamental developmental process, and test methods to identify interfering toxicants have been developed. By examining cell function endpoints, as in the ‘migration-inhibition of NCC (cMINC)’ assay, a… read more here.
Keywords: planar pcbs; pcbs; toxicity; structure ... See more keywords
Cardiac Neural Crest Cells: Their Rhombomeric Specification, Migration, and Association with Heart and Great Vessel Anomalies
Sign Up to like & getrecommendations! Published in 2020 at "Cellular and Molecular Neurobiology"
DOI: 10.1007/s10571-020-00863-w
Abstract: Outflow tract abnormalities are the most frequent congenital heart defects. These are due to the absence or dysfunction of the two main cell types, i.e., neural crest cells and secondary heart field cells that migrate… read more here.
Keywords: heart; migration; neural crest; crest cells ... See more keywords
Migratory Neural Crest Cells Phagocytose Dead Cells in the Developing Nervous System
Sign Up to like & getrecommendations! Published in 2019 at "Cell"
DOI: 10.1016/j.cell.2019.08.001
Abstract: During neural tube closure and spinal cord development, many cells die in both the central and peripheral nervous systems (CNS and PNS, respectively). However, myeloid-derived professional phagocytes have not yet colonized the trunk region during… read more here.
Keywords: cells phagocytose; nervous system; developing nervous; neural crest ... See more keywords
Mesenteric Neural Crest Cells Are the Embryological Basis of Skip Segment Hirschsprung’s Disease
Sign Up to like & getrecommendations! Published in 2020 at "Cellular and Molecular Gastroenterology and Hepatology"
DOI: 10.1016/j.jcmgh.2020.12.010
Abstract: Background & Aims Defective rostrocaudal colonization of the gut by vagal neural crest cells (vNCCs) results in Hirschsprung's disease (HSCR), which is characterized by aganglionosis in variable lengths of the distal bowel. Skip segment Hirschsprung’s… read more here.
Keywords: skip segment; segment; hirschsprung disease; neural crest ... See more keywords
Pdgf1aa regulates zebrafish neural crest cells migration through Hif-1 in an oxygen-independent manner
Sign Up to like & getrecommendations! Published in 2018 at "Mechanisms of development"
DOI: 10.1016/j.mod.2018.07.007
Abstract: The transcription factor Hif-1α regulates epithelial to mesenchymal transition and neural crest cell chemotaxis in Xenopus. Hif-1α is only stabilised under low oxygen levels, and the in vivo stabilisation of this factor in neural crest… read more here.
Keywords: crest cells; hif; oxygen independent; neural crest ... See more keywords
Neural crest cells utilize primary cilia to regulate ventral forebrain morphogenesis via Hedgehog-dependent regulation of oriented cell division.
Sign Up to like & getrecommendations! Published in 2017 at "Developmental biology"
DOI: 10.1016/j.ydbio.2017.09.026
Abstract: Development of the brain directly influences the development of the face via both physical growth and Sonic hedgehog (SHH) activity; however, little is known about how neural crest cells (NCCs), the mesenchymal population that comprise… read more here.
Keywords: primary cilia; wnt1 cre; neural crest; crest cells ... See more keywords