Brief exposure to small molecules allows induction of mouse embryonic fibroblasts into neural crest‐like precursors
Sign Up to like & getrecommendations! Published in 2017 at "Febs Letters"
DOI: 10.1002/1873-3468.12572
Abstract: In this study, we propose a novel method for inducing neuronal cells by briefly exposing them to small‐molecule cocktails in a step‐by‐step manner. Global gene expression analysis with immunohistochemical staining and calcium flux assays reveal… read more here.
Keywords: embryonic fibroblasts; brief exposure; exposure small; crest like ... See more keywords
Wnt/BMP mediated metabolic reprogramming preserves multipotency of neural crest like stem cells.
Sign Up to like & getrecommendations! Published in 2023 at "Stem cells"
DOI: 10.1093/stmcls/sxad001
Abstract: Neural Crest-like Stem cells resembling embryonic neural crest cells (NCs) can be derived from adult human tissues such as the epidermis. However, these cells lose their multipotency rapidly in culture limiting their expansion for clinical… read more here.
Keywords: like stem; neural crest; crest like; stem cells ... See more keywords