Selective antagonism of CRF1 receptor by a substituted pyrimidine
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DOI: 10.1007/s42000-019-00105-9
Abstract: The corticotrophin-releasing factor (CRF) and its type 1 receptor (CRF1R) regulate the hypothalamic-pituitary-adrenal axis, as well as other systems, thus playing a crucial role in the maintenance of homeostasis. Non-peptide CRF1R-selective antagonists exert therapeutic effects… read more here.
Keywords: crf1r; crf1r selective; non peptide; analog ... See more keywords