Optimization of cRGDfK ligand concentration on polymeric nanoparticles to maximize cancer targeting
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Industrial and Engineering Chemistry"
DOI: 10.1016/j.jiec.2019.09.006
Abstract: Abstract Optimization of ligand density on polymeric nanoparticles (PNPs) is critical for targeting solid tumors. Here, we prepared fluorescent cyanine 5.5 dye and cyclo(arginine–glycine–aspartic acid–phenylalanine–lysine) ligand-modified polyethylene glycol-poly(lactic-co-glycolic acid) (Cy 5.5-cRGDfK-PEG-PLGA) NPs with different ligand… read more here.
Keywords: polymeric nanoparticles; cancer targeting; crgdfk; concentration ... See more keywords
Theranostic potential of biodegradable polymeric nanoparticles with paclitaxel and curcumin against breast carcinoma.
Sign Up to like & getrecommendations! Published in 2021 at "Biomaterials science"
DOI: 10.1039/d1bm00370d
Abstract: In this study, integrin-mediated targeting and near-infrared fluorescence (NIRF) traceable polyethylene glycol-b-poly(lactic-co-glycolic acid) (PEG-PLGA)-based polymeric nanoparticles (NPs) were prepared to investigate the effects of paclitaxel (PTX) and curcumin (CUR) combination therapy on breast cancer. Cyclic… read more here.
Keywords: polymeric nanoparticles; breast; breast carcinoma; crgdfk ... See more keywords