Targeted overexpression of CRH receptor subtype 1 in central amygdala neurons: effect on alcohol-seeking behavior
Sign Up to like & getrecommendations! Published in 2018 at "Psychopharmacology"
DOI: 10.1007/s00213-018-4908-6
Abstract: RationaleThe corticotropin-releasing hormone (CRH) system is a key mediator of stress-induced responses in alcohol-seeking behavior. Recent research has identified the central nucleus of the amygdala (CeA), a brain region involved in the regulation of fear… read more here.
Keywords: cea; crhr1; effect; crh ... See more keywords
Pre-reproductive stress in adolescent female rats alters oocyte microRNA expression and offspring phenotypes: pharmacological interventions and putative mechanisms
Sign Up to like & getrecommendations! Published in 2021 at "Translational Psychiatry"
DOI: 10.1038/s41398-021-01220-1
Abstract: Pre-reproductive stress (PRS) to adolescent female rats alters anxiogenic behavior in first (F1)- and second-generation (F2) offspring and increases mRNA expression of corticotropin-releasing factor receptor type 1 ( Crhr1) in oocytes and in neonate offspring… read more here.
Keywords: adolescent female; crhr1; stress; expression ... See more keywords
Electroacupuncture alleviates anxiety and modulates amygdala CRH/CRHR1 signaling in single prolonged stress mice
Sign Up to like & getrecommendations! Published in 2022 at "Acupuncture in Medicine"
DOI: 10.1177/09645284211056352
Abstract: Background: Post-traumatic stress disorder (PTSD) is an anxiety-related psychiatric disorder, manifesting high comorbidity with anxiety disorders. Its underlying neurobiological mechanisms have been associated with hypothalamic–pituitary–adrenal (HPA) axis dysfunction and stress hormones. Corticotropin-releasing hormone (CRH) is… read more here.
Keywords: stress; sps mice; crh crhr1; crhr1 ... See more keywords
CRHR1 mediates the transcriptional expression of pituitary hormones and their receptors under hypoxia
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.893238
Abstract: Hypothalamus-pituitary-adrenal (HPA) axis plays critical roles in stress responses under challenging conditions such as hypoxia, via regulating gene expression and integrating activities of hypothalamus-pituitary-targets cells. However, the transcriptional regulatory mechanisms and signaling pathways of hypoxic… read more here.
Keywords: stress; transcription; crhr1; expression ... See more keywords
Dissociable Role of Corticotropin Releasing Hormone Receptor Subtype 1 on Dopaminergic and D1 Dopaminoceptive Neurons in Cocaine Seeking Behavior
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Behavioral Neuroscience"
DOI: 10.3389/fnbeh.2017.00221
Abstract: The ability of many drugs of abuse, including cocaine, to mediate reinforcement and drug-seeking behaviors is in part mediated by the corticotropin-releasing hormone (CRH) system, in which CRH exerts its effects partly via the CRH… read more here.
Keywords: crhr1; corticotropin releasing; role; mice ... See more keywords