A CRHR1 antagonist prevents synaptic loss and memory deficits in a trauma-induced delirium-like syndrome
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DOI: 10.1038/s41380-020-0659-y
Abstract: Older patients with severe physical trauma are at high risk of developing neuropsychiatric syndromes with global impairment of cognition, attention, and consciousness. We employed a thoracic trauma (TxT) mouse model and thoroughly analyzed age-dependent spatial… read more here.
Keywords: synaptic loss; trauma induced; crhr1 antagonist; induced delirium ... See more keywords