MicroRNA expression profiles in patients with acute Crimean Congo hemorrhagic fever reveal possible adjustments to cellular pathways
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DOI: 10.1002/jmv.24667
Abstract: Several viral diseases are associated with altered microRNA (miRNA) expression, which can provide vital information about how cellular pathways respond to infection. However, the miRNA profile of Crimean Congo Hemorrhagic Fever (CCHFV) infections are not… read more here.
Keywords: hemorrhagic fever; congo hemorrhagic; expression; crimean congo ... See more keywords
A case of Crimean‐Congo hemorrhagic fever with the bacteremia of Clostridium perfringens
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DOI: 10.1002/jmv.26715
Abstract: Crimean‐Congo hemorrhagic fever (CCHF) is a worldwide tick‐borne viral infection in humans. The aim of the study is to report a case of a female patient with severe CCHF with the bacteremia of Clostridium perfringens.… read more here.
Keywords: bacteremia clostridium; fever; hemorrhagic fever; case ... See more keywords
Expression and characterization of codon-optimized Crimean-Congo hemorrhagic fever virus Gn glycoprotein in insect cells
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DOI: 10.1007/s00705-017-3315-3
Abstract: Crimean-Congo hemorrhagic fever virus (CCHFV) is a major cause of tick-borne viral hemorrhagic disease in the world. Despite of its importance as a deadly pathogen, there is currently no licensed vaccine against CCHF disease. The… read more here.
Keywords: hemorrhagic; cchfv; expression; congo hemorrhagic ... See more keywords
Evaluation of the associations between endothelial dysfunction, inflammation and coagulation in Crimean-Congo hemorrhagic fever patients
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DOI: 10.1007/s00705-017-3653-1
Abstract: Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne zoonotic viral disease. The aim of this study was to evaluate the association between inflammation, coagulation and endothelial dysfunction in CCHF. The study population consisted of 40 patients… read more here.
Keywords: coagulation; cchf; dysfunction; inflammation ... See more keywords
Sero-Epidemiological Survey of Crimean-Congo Hemorrhagic Fever among the Human Population of the Punjab Province in Pakistan
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DOI: 10.1007/s12250-020-00195-5
Abstract: Crimean-Congo hemorrhagic fever (CCHF), caused by the CCHF virus (CCHFV), is a tick-borne zoonotic infection characterized by myalgia, high-grade fever (> 38 ℃), headache, nausea, bleeding from the body cavities, and in 10%–50% of cases,… read more here.
Keywords: sero epidemiological; fever; hemorrhagic fever; congo hemorrhagic ... See more keywords
Viral replicon particles protect IFNAR-/- mice against lethal Crimean-Congo hemorrhagic fever virus challenge three days after vaccination.
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DOI: 10.1016/j.antiviral.2021.105090
Abstract: Crimean-Congo hemorrhagic fever virus (CCHFV) causes mild to severe and fatal disease in humans. Person-to-person transmission is common, necessitating the availability of rapidly deliverable therapeutic and prophylactic interventions to mitigate CCHFV spread. Previously, we showed… read more here.
Keywords: hemorrhagic fever; fever virus; viral replicon; mice ... See more keywords
Protective neutralizing antibodies from human survivors of Crimean-Congo hemorrhagic fever
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DOI: 10.1016/j.cell.2021.05.001
Abstract: Crimean-Congo hemorrhagic fever virus (CCHFV) is a World Health Organization priority pathogen. CCHFV infections cause a highly lethal hemorrhagic fever for which specific treatments and vaccines are urgently needed. Here, we characterize the human immune… read more here.
Keywords: hemorrhagic; hemorrhagic fever; cchfv; protective neutralizing ... See more keywords
Effects of Paraoxonase-1 variants on course of severity and mortality of Crimean-Congo hemorrhagic fever.
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DOI: 10.1016/j.gene.2018.11.059
Abstract: Crimean-Congo hemorrhagic fever (CCHF) is an acute viral hemorrhagic fever caused by Crimean Congo hemorrhagic fever virus (CCHFV). Paraoxonase-1 (PON1) is a high density lipoprotein (HDL)-binding protein which defense the body against oxidative stress. To… read more here.
Keywords: hemorrhagic; hemorrhagic fever; congo hemorrhagic; crimean congo ... See more keywords
Co-circulation of Crimean-Congo Hemorrhagic Fever virus strains Asia 1 and 2 between the border of Iran and Pakistan
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DOI: 10.1016/j.heliyon.2017.e00439
Abstract: Crimean-Congo Hemorrhagic Fever (CCHF) is a tick-borne viral disease that is transmitted by numerous species of ticks, which serve both as a reservoir and vector of CCHF virus (CCHFV). Molecular and serological tests were undertaken… read more here.
Keywords: hemorrhagic fever; congo hemorrhagic; crimean congo;
Crimean-Congo hemorrhagic fever in pregnancy: A systematic review and case series from Russia, Kazakhstan and Turkey
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DOI: 10.1016/j.ijid.2017.02.019
Abstract: Highlights • CCHF in pregnancy is rare but has high rates of maternal (34%) and fetal mortality (59%).• Maternal hemorrhage is associated with maternal and fetal/neonatal death.• Nosocomial transmission of CCHF from 6/37 index pregnant… read more here.
Keywords: pregnancy; hemorrhagic fever; fever pregnancy; pregnancy systematic ... See more keywords
Hitit Index to distinguish patients with and without Crimean-Congo hemorrhagic fever.
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DOI: 10.1016/j.ttbdis.2019.05.010
Abstract: Crimean-Congo hemorrhagic fever (CCHF) is fatal. Therefore, it is very important to use an inexpensive, easily accessible, quick and accurate screening index based on clinical signs and laboratory parameters to identify patients suspected of having… read more here.
Keywords: index; hitit index; hemorrhagic fever; congo hemorrhagic ... See more keywords