Genome editing in Streptococcus mutans through selfâtargeting CRISPR arrays
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Oral Microbiology"
DOI: 10.1111/omi.12247
Abstract: Streptococcus mutans is the primary etiological agent of human dental caries. Its major virulence factors, glucosyltransferases (Gtfs), utilize sucrose to synthesize extracellular polysaccharides (EPS), leading to the formation of dental plaque biofilm. The current study… read more here.
Keywords: crispr; targeting crispr; self targeting; crispr arrays ... See more keywords
Long reads reveal the diversification and dynamics of CRISPR reservoir in microbiomes
Sign Up to like & getrecommendations! Published in 2019 at "BMC Genomics"
DOI: 10.1186/s12864-019-5922-8
Abstract: BackgroundSequencing of microbiomes has accelerated the characterization of the diversity of CRISPR-Cas immune systems. However, the utilization of next generation short read sequences for the characterization of CRISPR-Cas dynamics remains limited due to the repetitive… read more here.
Keywords: spacer; crispr; long reads; crispr cas ... See more keywords
Transcriptional analysis of CRISPR I-B arrays of Leptospira interrogans serovar Lai and its processing by Cas6
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.960559
Abstract: In the genome of various Leptospira interrogans serovars, the subtype I-B locus of CRISPR-Cas possesses either one or multiple CRISPR arrays. In silico database (CRISPRCasdb) for predicting CRISPR-Cas reveals seven CRISPR arrays in L. interrogans… read more here.
Keywords: serovar lai; leptospira interrogans; crispr arrays; crispr ... See more keywords