Genome editing in Streptococcus mutans through self‐targeting CRISPR arrays
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Oral Microbiology"
DOI: 10.1111/omi.12247
Abstract: Streptococcus mutans is the primary etiological agent of human dental caries. Its major virulence factors, glucosyltransferases (Gtfs), utilize sucrose to synthesize extracellular polysaccharides (EPS), leading to the formation of dental plaque biofilm. The current study… read more here.
Keywords: crispr; targeting crispr; self targeting; crispr arrays ... See more keywords
Long reads reveal the diversification and dynamics of CRISPR reservoir in microbiomes
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DOI: 10.1186/s12864-019-5922-8
Abstract: BackgroundSequencing of microbiomes has accelerated the characterization of the diversity of CRISPR-Cas immune systems. However, the utilization of next generation short read sequences for the characterization of CRISPR-Cas dynamics remains limited due to the repetitive… read more here.
Keywords: spacer; crispr; long reads; crispr cas ... See more keywords
Transcriptional analysis of CRISPR I-B arrays of Leptospira interrogans serovar Lai and its processing by Cas6
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DOI: 10.3389/fmicb.2022.960559
Abstract: In the genome of various Leptospira interrogans serovars, the subtype I-B locus of CRISPR-Cas possesses either one or multiple CRISPR arrays. In silico database (CRISPRCasdb) for predicting CRISPR-Cas reveals seven CRISPR arrays in L. interrogans… read more here.
Keywords: serovar lai; leptospira interrogans; crispr arrays; crispr ... See more keywords
Assessing spacer acquisition rates in E. coli type I-E CRISPR arrays
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DOI: 10.3389/fmicb.2024.1498959
Abstract: CRISPR/Cas is an adaptive defense mechanism protecting prokaryotes from viruses and other potentially harmful genetic elements. Through an adaptation process, short “spacer” sequences, captured from these elements and incorporated into a CRISPR array, provide target… read more here.
Keywords: acquisition rates; crispr arrays; crispr; coli type ... See more keywords