Mitochondrial import, health and mtDNA copy number variability seen when using type II and type V CRISPR effectors
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DOI: 10.1242/jcs.248468
Abstract: ABSTRACT Current methodologies for targeting the mitochondrial genome for research and/or therapy development in mitochondrial diseases are restricted by practical limitations and technical inflexibility. A molecular toolbox for CRISPR-mediated mitochondrial genome editing is desirable, as… read more here.
Keywords: copy number; crispr; mitochondrial import; crispr effectors ... See more keywords