CRISPR gene-editing creates wave of exotic model organisms
Sign Up to like & getrecommendations! Published in 2019 at "Nature"
DOI: 10.1038/d41586-019-01300-9
Abstract: But the practical challenges of breeding and maintaining unconventional lab animals persist.But the practical challenges of breeding and maintaining unconventional lab animals persist. read more here.
Keywords: editing creates; gene editing; crispr gene; creates wave ... See more keywords
CRISPR gene editing – what are the possibilities for respiratory medicine?
Sign Up to like & getrecommendations! Published in 2022 at "Expert Review of Respiratory Medicine"
DOI: 10.1080/17476348.2022.2056021
Abstract: In his 1959 Nobel Lecture, Joshua Lederberg discusses the specific mutagen, an agent that could ‘penetrate to a given gene, recognize and modify it in a specific way’, as the ignis fatuus of genetics, a… read more here.
Keywords: medicine; respiratory medicine; crispr; medicine crispr ... See more keywords
CRISPR Gene Editing of Virulent Bacteriophage ICP1.
Sign Up to like & getrecommendations! Published in 2023 at "Cold Spring Harbor protocols"
DOI: 10.1101/pdb.prot108316
Abstract: Tools for site-directed mutagenesis of virulent bacteriophages (phages; viruses of bacteria) have traditionally lagged those for bacteria, hindering their study. CRISPR gene editing represents a new and highly efficient method for editing virulent phage genomes.… read more here.
Keywords: gene editing; section outlines; crispr gene; icp1 ... See more keywords
Evolutionary dynamics of CRISPR gene drives
Sign Up to like & getrecommendations! Published in 2017 at "Science Advances"
DOI: 10.1126/sciadv.1601964
Abstract: Previous CRISPR gene drives should undergo limited spread due to resistance, and a potential solution is presented. The alteration of wild populations has been discussed as a solution to a number of humanity’s most pressing… read more here.
Keywords: crispr gene; dynamics crispr; gene; evolutionary dynamics ... See more keywords
Modeling the efficacy of CRISPR gene drive for snail immunity on schistosomiasis control
Sign Up to like & getrecommendations! Published in 2022 at "PLOS Neglected Tropical Diseases"
DOI: 10.1371/journal.pntd.0010894
Abstract: CRISPR gene drives could revolutionize the control of infectious diseases by accelerating the spread of engineered traits that limit parasite transmission in wild populations. Gene drive technology in mollusks has received little attention despite the… read more here.
Keywords: gene drive; immunity; schistosomiasis; crispr gene ... See more keywords
CRISPR Gene Therapy: Applications, Limitations, and Implications for the Future
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2020.01387
Abstract: A series of recent discoveries harnessing the adaptive immune system of prokaryotes to perform targeted genome editing is having a transformative influence across the biological sciences. The discovery of Clustered Regularly Interspaced Short Palindromic Repeats… read more here.
Keywords: therapy applications; gene therapy; crispr gene; gene ... See more keywords
Commentary: CRISPR gene editing for inherited retinal dystrophies: Towards clinical translation
Sign Up to like & getrecommendations! Published in 2022 at "Indian Journal of Ophthalmology"
DOI: 10.4103/ijo.ijo_1010_22
Abstract: The clustered regularly interspaced short palindromic repeats (CRISPR) system won the Nobel Prize in 2020. What makes this technology intriguing is the ability of the CRISPR/ Cas9 effector molecules to identify and bind to specific… read more here.
Keywords: editing inherited; commentary crispr; crispr; gene editing ... See more keywords