Modified screening of MYC promotor region elements using the CRISPR library in ovarian cancer
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Ovarian Research"
DOI: 10.1186/s13048-025-01644-z
Abstract: Ovarian cancer remains one of the most lethal gynecological malignancies owing to its high recurrence rate and chemotherapeutic resistance. MYC is a well-known proto-oncogene that is frequently amplified in ovarian cancer and has been implicated… read more here.
Keywords: cancer; using crispr; promoter; crispr library ... See more keywords
Efficient Identification of the MYC Regulator with the Use of the CRISPR Library and Context-Matched Database Screenings
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DOI: 10.3390/ijms23147723
Abstract: MYC is a major oncogene that plays an important role in cell proliferation in human cancers. Therefore, the mechanism behind MYC regulation is a viable therapeutic target for the treatment of cancer. Comprehensive and efficient… read more here.
Keywords: efficient identification; matched database; myc; crispr library ... See more keywords