CRISPR and transposon in vivo screens for cancer drivers and therapeutic targets
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DOI: 10.1186/s13059-020-02118-9
Abstract: Human cancers harbor substantial genetic, epigenetic, and transcriptional changes, only some of which drive oncogenesis at certain times during cancer evolution. Identifying the cancer-driver alterations amongst the vast swathes of “passenger” changes still remains a… read more here.
Keywords: crispr transposon; cancer drivers; vivo screens; screens cancer ... See more keywords