Articles with "crispra screen" as a keyword



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Genome-Scale CRISPRa Screen Identifies Novel Factors for Cellular Reprogramming

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Published in 2019 at "Stem Cell Reports"

DOI: 10.1016/j.stemcr.2019.02.010

Abstract: Summary Primed epiblast stem cells (EpiSCs) can be reverted to a pluripotent embryonic stem cell (ESC)-like state by expression of single reprogramming factor. We used CRISPR activation to perform a genome-scale, reprogramming screen in EpiSCs… read more here.

Keywords: genome scale; crispra screen; screen identifies; scale crispra ... See more keywords