Efficient reduction of carbamazepine using UV-activated sulfite: Assessment of critical process parameters and elucidation of radicals involved
Sign Up to like & getrecommendations! Published in 2021 at "Chemical Engineering Journal"
DOI: 10.1016/j.cej.2020.126403
Abstract: Abstract For a successful reclamation of aquatic systems, advanced reduction processes (ARP) have recently attracted a lot of attention for the elimination of emerging pharmaceutical compounds. This study investigates the synergistic effect between UV and… read more here.
Keywords: reduction; degradation; critical process; process ... See more keywords
Critical process parameters in manufacturing of liposomal formulations of amphotericin B.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2019.04.052
Abstract: Identifying the critical process parameters (CPPs) of a complex drug product manufacture and the associated impact on critical quality attributes (CQAs) is essential to the development and quality control of both new and generic drugs.… read more here.
Keywords: critical process; drug; process; process parameters ... See more keywords
Application of statistical design to evaluate critical process parameters and optimize formulation technique of polymeric nanoparticles
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DOI: 10.1098/rsos.190896
Abstract: In advanced medication, drug-loaded polymeric nanoparticles (NPs) appeared as a novel drug delivery system with lots of advantages over conventional medicines. Despite all the advantages, NPs do not gain popularity for manufacturing hurdles. The study… read more here.
Keywords: polymeric nanoparticles; statistical design; critical process; model ... See more keywords
An Improved Impact Ratio for Identifying Critical Process Parameters in Pharmaceutical Manufacturing Processes
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DOI: 10.5731/pdajpst.2021.012662
Abstract: The identification of critical process parameters in biologics and small molecule process development is a key element of quality by design. The objectivity and consistency of procedures to identify critical process parameters can be improved… read more here.
Keywords: process parameters; process; impact ratio; critical process ... See more keywords