Impact of scaffold granule size use in Masquelet technique on periosteal reaction: a study in rat femur critical size bone defect model
Sign Up to like & getrecommendations! Published in 2020 at "European Journal of Trauma and Emergency Surgery"
DOI: 10.1007/s00068-020-01516-9
Abstract: The Masquelet technique for the treatment of large bone defects is a two-stage procedure based on an induced membrane. Compared to mature periosteum, the induced membrane differs significantly. However, both play a crucial role in… read more here.
Keywords: technique; induced membrane; masquelet; critical size ... See more keywords
Healing mechanism and osteogenic capacity of bovine bone mineral—human amniotic mesenchymal stem cell and autogenous bone graft in critical size mandibular defect
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Oral and Maxillofacial Surgery"
DOI: 10.1016/j.ijom.2017.02.701
Abstract: Experiments on maxillofacial bone tissue engineering showed the promising result; however, its healing mechanisms and effectiveness had not been fully understood. The aim of this study is to compare the bone healing mechanism and osteogenic… read more here.
Keywords: critical size; bone; bbm hamsc; bone graft ... See more keywords
Optimal Scaling of Critical Size for Metamorphosis in the Genus Drosophila
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DOI: 10.1016/j.isci.2019.09.033
Abstract: Summary Juveniles must reach a critical body size to become a mature adult. Molecular determinants of critical size have been studied, but the evolutionary importance of critical size is still unclear. Here, using nine fly… read more here.
Keywords: size metamorphosis; metamorphosis genus; critical size; size ... See more keywords
Self-Adhesive Hydrogel Biomimetic Periosteum to Promote Critical-Size Bone Defect Repair via Synergistic Osteogenesis and Angiogenesis.
Sign Up to like & getrecommendations! Published in 2022 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.2c08400
Abstract: The periosteum plays an important role in the regeneration of critical-size bone defects, with functions of recruiting multiple cells, accelerating vascular network reconstruction, and guiding bone tissue regeneration. However, these functions cannot be easily implemented… read more here.
Keywords: biomimetic periosteum; bone; periosteum; critical size ... See more keywords
A preclinical large-animal model for the assessment of critical-size load-bearing bone defect reconstruction
Sign Up to like & getrecommendations! Published in 2020 at "Nature Protocols"
DOI: 10.1038/s41596-019-0271-2
Abstract: Critical-size bone defects, which require large-volume tissue reconstruction, remain a clinical challenge. Bone engineering has the potential to provide new treatment concepts, yet clinical translation requires anatomically and physiologically relevant preclinical models. The ovine critical-size… read more here.
Keywords: reconstruction; bone defect; critical size; bone ... See more keywords
Chitosan-Graphene Oxide 3D scaffolds as Promising Tools for Bone Regeneration in Critical-Size Mouse Calvarial Defects
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-16599-5
Abstract: Limited self-regenerating capacity of human skeleton makes the reconstruction of critical size bone defect a significant challenge for clinical practice. Aimed for regenerating bone tissues, this study was designed to investigate osteogenic differentiation, along with… read more here.
Keywords: graphene oxide; cht; mouse calvarial; critical size ... See more keywords
Bone Healing Evaluation in Critical-Size Defects Treated With Xenogenous Bone Plus Porcine Collagen
Sign Up to like & getrecommendations! Published in 2017 at "Implant Dentistry"
DOI: 10.1097/id.0000000000000572
Abstract: Purpose: This study aimed to evaluate the osteoconductive features of Bio-Oss Collagen in large critical-size defects (8 mm). Materials and Methods: Thirty-six adult Wistar Albinus male adult rats were carried out a critical-size defect with… read more here.
Keywords: collagen; size defects; bio oss; critical size ... See more keywords
Critical Size Defects for Bone Regeneration Experiments in the Dog Mandible: A Systematic Review
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DOI: 10.1097/id.0000000000000713
Abstract: Objectives: To perform a systematic literature review of studies involving critical size defects (CSDs) in the dog mandible and calvarium to find out the common characteristics of CSDs. Materials and Methods: Internet search of the… read more here.
Keywords: size defects; dog mandible; critical size; review ... See more keywords
Evolution of reduced minimum critical size as a response to selection for rapid pre-adult development in Drosophila melanogaster
Sign Up to like & getrecommendations! Published in 2020 at "Royal Society Open Science"
DOI: 10.1098/rsos.191910
Abstract: Adult body size in holometabolus insects is directly proportional to the time spent during the larval period. The larval duration can be divided into two parts: (i) pre-critical duration—time required to attain a critical size/critical… read more here.
Keywords: pre adult; critical size; size; development ... See more keywords
Microarray gene expression during early healing of GBR‐treated calvarial critical size defects
Sign Up to like & getrecommendations! Published in 2017 at "Clinical Oral Implants Research"
DOI: 10.1111/clr.12949
Abstract: OBJECTIVES To investigate the gene expression and molecular pathways implicated in the regulation of the osseous healing process following guided bone regeneration (GBR). MATERIAL AND METHODS Six 6-month-old Wistar male rats were used. Standardized 5-mm… read more here.
Keywords: size defects; gene expression; gbr; critical size ... See more keywords
Evaluation of perforated demineralized dentin scaffold on bone regeneration in critical‐size sheep iliac defects
Sign Up to like & getrecommendations! Published in 2017 at "Clinical Oral Implants Research"
DOI: 10.1111/clr.13000
Abstract: OBJECTIVES Regenerating critical-size bone injury is a major problem that continues to inspire the design of new graft materials. Therefore, tissue engineering has become a novel approach for targeting bone regeneration applications. Human teeth are… read more here.
Keywords: critical size; bone; demineralized dentin; bone regeneration ... See more keywords