Critically short telomeres and toxicity of chemotherapy in early breast cancer
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DOI: 10.18632/oncotarget.15592
Abstract: Cumulative toxicity from weekly paclitaxel (myalgia, peripheral neuropathy, fatigue) compromises long-term administration. Preclinical data suggest that the burden of critically short telomeres (< 3 kilobases, CSTs), but not average telomere length by itself, accounts for… read more here.
Keywords: breast cancer; toxicity; critically short; average telomere ... See more keywords