An Insight on the Pathways Involved in Crizotinib and Sunitinib Induced Hepatotoxicity in HepG2 Cells and Animal Model
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DOI: 10.3389/fonc.2022.749954
Abstract: Both crizotinib and sunitinib, novel orally-active multikinase inhibitors, exhibit antitumor activity and extend the survival of patients with a malignant tumor. However, some patients may suffer liver injury that can further limit the clinical use… read more here.
Keywords: sunitinib induced; crizotinib sunitinib; sunitinib; oxidative stress ... See more keywords