C-Terminal End-Directed Protein Elimination by CRL2Â Ubiquitin Ligases.
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DOI: 10.1016/j.molcel.2018.04.006
Abstract: The proteolysis-assisted protein quality control system guards the proteome from potentially detrimental aberrant proteins. How miscellaneous defective proteins are specifically eliminated and which molecular characteristics direct them for removal are fundamental questions. We reveal a… read more here.
Keywords: end degrons; crl2 ubiquitin; protein elimination; end ... See more keywords