Genetic and Epigenetic Mechanisms Deregulate the CRL2pVHL Complex in Hepatocellular Carcinoma
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DOI: 10.3389/fgene.2022.910221
Abstract: Dysregulation of ubiquitin-proteasome pathway genes through copy number alteration, promoter hypomethylation, and miRNA deregulation is involved in cancer development and progression. Further characterizing alterations in these genes may uncover novel drug targets across a range… read more here.
Keywords: hepatocellular carcinoma; crl2pvhl; component genes; mechanisms ... See more keywords