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Published in 2025 at "Communications Biology"
DOI: 10.1038/s42003-025-08988-8
Abstract: Trio is a neuronally expressed, Rac1- and RhoA-activating RhoGEF, that is required for neurodevelopment. Mutations affecting the Rac1-activating GEF domain of Trio are associated with profound neurodevelopmental delay and Trio knock-out is embryonic lethal. Although…
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Keywords:
axon branching;
regulate axon;
trio;
crmp2 regulate ... See more keywords