Amyotrophic Lateral Sclerosis, Neuroinflammation, and Cromolyn.
Sign Up to like & getrecommendations! Published in 2020 at "Clinical therapeutics"
DOI: 10.1016/j.clinthera.2020.01.010
Abstract: Amyotrophic lateral sclerosis (ALS) is an upper motor neuron disease with an unknown pathogenesis and no effective treatment. A recent study found that treatment of a mouse model of ALS (TgSOD1 mice) intraperitoneally with the… read more here.
Keywords: mast cells; amyotrophic lateral; lateral sclerosis; cromolyn ... See more keywords
Cromolyn inhibits the secretion of inflammatory cytokines by human microglia (HMC3)
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-85702-8
Abstract: Cromolyn is a known mast cell stabilizer and is approved for treatment of asthma and for other allergic indications. Cromolyn, in a new redesigned dry powder formulation, is being tested in a pivotal clinical trial… read more here.
Keywords: effect cromolyn; secretion; inhibits secretion; cromolyn ... See more keywords