Thieme Chemistry Journals Awardees – Where Are They Now?Carbene Organocatalysis for Stetter, Benzoin, Domino, and Ring-Expansion Reactions
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DOI: 10.1055/s-0036-1588675
Abstract: N-Heterocyclic carbene catalysis allows the rapid formation of functionalized carbon–carbon bonds. Our group has spent the previous decade focusing on broadening practical applications of this type of catalysis. The design and discovery of novel reactivities… read more here.
Keywords: cross benzoin; expansion; ring expansion; expansion reactions ... See more keywords
Chemoselective Intermolecular Cross-Benzoin Reaction of Aliphatic Aldehydes and Isatins via N-Heterocyclic Carbene Catalysis
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DOI: 10.1055/s-0037-1612250
Abstract: An N-heterocyclic carbene (NHC)-catalyzed chemoselective intermolecular cross-benzoin reaction of aliphatic aldehydes with isatins is developed, affording biologically important 3-substituted 3-hydroxyoxindoles (on gram scale) in moderate to good yields (46–90%). The employment of a morpholinone-derived pentafluorophenyl-substituted… read more here.
Keywords: cross benzoin; reaction; heterocyclic carbene; benzoin reaction ... See more keywords