Cobalt‐Catalyzed Cross‐Couplings and Electrophilic Aminations using Organozinc Pivalates
Sign Up to like & getrecommendations! Published in 2019 at "ChemCatChem"
DOI: 10.1002/cctc.201900070
Abstract: Transition metal catalyzed cross‐couplings are essential methods in organic synthesis. Due to their comparable low toxicity and price, cobalt‐salts offer a useful alternative to other common metal‐catalysts (e. g. palladium‐complexes). In this review, we report that… read more here.
Keywords: cross couplings; organozinc pivalates; aminations using; catalyzed cross ... See more keywords
Cobalt-Catalyzed Cross-Couplings between Alkyl Halides and Grignard Reagents.
Sign Up to like & getrecommendations! Published in 2020 at "Accounts of chemical research"
DOI: 10.1021/acs.accounts.0c00238
Abstract: ConspectusMetal-catalyzed cross-couplings have emerged as essential tools for the construction of C-C bonds. The identification of efficient catalytic systems as well as large substrate scope made these cross-couplings key reactions to access valuable molecules ranging… read more here.
Keywords: cross couplings; alkyl halides; grignard reagents; cobalt catalyzed ... See more keywords
Nickel-Catalyzed Ligand-Controlled Selective Reductive Cyclization/Cross-Couplings.
Sign Up to like & getrecommendations! Published in 2023 at "Accounts of chemical research"
DOI: 10.1021/acs.accounts.2c00771
Abstract: ConspectusThe use of quaternary stereocenters during lead candidate optimization continues to grow because of improved physiochemical and pharmacokinetic profiles of compounds with higher sp3 fraction. Pd-catalyzed redox-neutral alkene difunctionalization involving carbopalladation of alkenes followed by… read more here.
Keywords: cross coupling; cross couplings; ligand; cross ... See more keywords
Accessing Aliphatic Amines in C-C Cross-Couplings by Visible Light/Nickel Dual Catalysis.
Sign Up to like & getrecommendations! Published in 2021 at "Organic letters"
DOI: 10.1021/acs.orglett.1c01207
Abstract: A general aminoalkylation of aryl halides was developed, overcoming intolerance of free amines in nickel-mediated C-C coupling. This transformation features broad functional group tolerance and high efficiency. Taking advantage of the fast desilylation of α-silylamines… read more here.
Keywords: cross couplings; couplings visible; accessing aliphatic; visible light ... See more keywords
Automated, Capsule-Based Suzuki-Miyaura Cross Couplings.
Sign Up to like & getrecommendations! Published in 2023 at "Organic letters"
DOI: 10.1021/acs.orglett.3c01057
Abstract: The development of an automated process for Suzuki-Miyaura cross couplings is described, in which the complete reaction, workup, and product isolation are effected automatically with no user involvement, aside from loading of the starting materials… read more here.
Keywords: cross couplings; suzuki miyaura; miyaura cross;
A Micellar Catalysis Strategy for Suzuki–Miyaura Cross-Couplings of 2-Pyridyl MIDA Boronates: No Copper, in Water, Very Mild Conditions
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DOI: 10.1021/acscatal.7b03241
Abstract: Suzuki–Miyaura (SM) cross-couplings of 2-pyridyl MIDA boronates can be successfully carried out in the complete absence of copper by attenuation of the Lewis basicity associated with the pyridyl nitrogen using selected substituents (e.g., fluorine or… read more here.
Keywords: suzuki miyaura; cross couplings; catalysis;
Nickel-catalyzed enantioselective electroreductive cross-couplings
Sign Up to like & getrecommendations! Published in 2020 at "Organic chemistry frontiers"
DOI: 10.1039/d0qo00901f
Abstract: Ni-Catalyzed reductive cross-coupling of two electrophiles has recently evolved into a powerful means for building diverse carbon–carbon bonds in an enantioselective manner. However, this strategy usually requires the use of excessive metal powder as a… read more here.
Keywords: cross couplings; enantioselective electroreductive; electroreductive cross; cross ... See more keywords
What can reaction databases teach us about Buchwald–Hartwig cross-couplings?
Sign Up to like & getrecommendations! Published in 2020 at "Chemical Science"
DOI: 10.1039/d0sc04074f
Abstract: Despite the widespread and increasing usage of Pd-catalyzed C–N cross couplings, finding good conditions for these reactions can be challenging. Practitioners mostly rely on few methodology studies or anecdotal experience. This is surprising, since the… read more here.
Keywords: cross couplings; buchwald hartwig; reaction; data driven ... See more keywords
A palladium polyaniline complex: a simple and efficient catalyst for batch and flow Suzuki-Miyaura cross-couplings.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc04051d
Abstract: A novel palladium polyaniline complex (Pd@PANI) was synthesized via a one-pot method using a low concentration of hydrogen peroxide (3 wt%) as a mild oxidant. Pd@PANI was employed to catalyze Suzuki-Miyaura cross-couplings with 0.11 ppm… read more here.
Keywords: cross couplings; polyaniline complex; suzuki miyaura; palladium polyaniline ... See more keywords
Recent Advances in Cross-Couplings of Functionalized Organozinc Reagents
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DOI: 10.1055/a-1589-0150
Abstract: Cross-couplings involving organozinc reagents require usually a Pd-catalysis (Negishi cross-coupling), however, uncatalyzed cross-couplings of zinc organometallics proceed well in the absence of transition-metal catalysts with reactive electrophiles such as benzal 1,1-diacetates, benzhydryl acetates, and iminium… read more here.
Keywords: cross couplings; couplings functionalized; recent advances; advances cross ... See more keywords
Nuclear symmetry energy with mesonic cross-couplings in the effective chiral model
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DOI: 10.1103/physrevc.96.035803
Abstract: The effective chiral model is extended by introducing the contributions from the cross-couplings between isovector and isoscalar mesons. These cross-couplings are found to be instrumental in improving the density content of the nuclear symmetry energy.… read more here.
Keywords: cross couplings; symmetry energy; nuclear symmetry; effective chiral ... See more keywords